Recombinant Human Isoleucine--tRNA ligase, mitochondrial (IARS2), partial

中文名稱：

人IARS2重組蛋白
貨號(hào)：

CSB-YP868313HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人IARS2重組蛋白
貨號(hào)：

CSB-EP868313HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人IARS2重組蛋白
貨號(hào)：

CSB-EP868313HU-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人IARS2重組蛋白
貨號(hào)：

CSB-BP868313HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人IARS2重組蛋白
貨號(hào)：

CSB-MP868313HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

IARS2
Uniprot No.：

Q9NSE4
別名：

2010002H18Rik; C79125; EC 6.1.1.5; FLJ10326; Iars2; IleRS; isoleucine tRNA ligase 2, mitochondrial; isoleucine tRNA ligase, mitochondrial; isoleucine tRNA synthetase 2, mitochondrial; Isoleucine--tRNA ligase; isoleucine-tRNA synthetase 2; isoleucyl tRNA synthetase 2, mitochondrial; Isoleucyl-tRNA synthetase; MGC63429; mitochondrial; mitochondrial isoleucine tRNA synthetase; rCG_20084; RGD1311857; SYIM_HUMAN
種屬：

Homo sapiens (Human)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

基因功能參考文獻(xiàn)：
1. IARS2 silencing induced NSCLC cells growth inhibition, cell cycle arrest and promoted cell apoptosis PMID: 26639235
2. Patients with this very rare mutation present with a myriad of ocular findings, including infantile cataract, neurotrophic keratitis, corneal opacification, and orbital myopathy. PMID: 27078007
3. The expression of IARS2 gene is different in human colon cancer and surrounding tissues. IARS2 gene is probably a cancer-promoting gene PMID: 26722399
4. This study is the first report of clinical findings associated with IARS2 mutations. PMID: 25130867
相關(guān)疾?。?/div>
Cataracts, growth hormone deficiency, sensory neuropathy, sensorineural hearing loss, and skeletal dysplasia (CAGSSS)
亞細(xì)胞定位：

Mitochondrion matrix.
蛋白家族：

Class-I aminoacyl-tRNA synthetase family
數(shù)據(jù)庫鏈接：

HGNC: 29685

OMIM: 612801

KEGG: hsa:55699

STRING: 9606.ENSP00000303279

UniGene: Hs.262823