Recombinant Human Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (GBGT1), partial

中文名稱：

人GBGT1重組蛋白
貨號：

CSB-YP009296HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人GBGT1重組蛋白
貨號：

CSB-EP009296HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人GBGT1重組蛋白
貨號：

CSB-EP009296HU-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人GBGT1重組蛋白
貨號：

CSB-BP009296HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人GBGT1重組蛋白
貨號：

CSB-MP009296HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

GBGT1
Uniprot No.：

Q8N5D6
別名：

3-N-acetylgalactosaminyltransferase 1; A3GALNT; EC=2.4.1.-; Forssman glycolipid synthase-like protein; Forssman glycolipid synthetase (FS); Forssman synthetase; FS; GBGT1; GBGT1_HUMAN; Globoside alpha-1; globoside alpha-1,3-N-acetylgalactosaminyltransferase 1; glycolipid synthase-like protein; RP11-326L24.6; UNQ2513; UNQ2513/PRO6002
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Has lost the ability to synthesize Forssman glycolipid antigen (FORS1/FG). Might have acquired an alternative function in glycosphingolipid metabolism, but it remains to be established. It appears to have drifted more slowly than confirmed pseudogenes in the glycosyltransferase 6 family, suggesting that it has remained under evolutionary pressure.
基因功能參考文獻(xiàn)：
1. GBGT1 expression is epigenetically silenced through promoter hypermethylation in ovarian cancer. PMID: 25294702
2. The Fs synthase gene, GBGT1, in A(pae) individuals encoded an arginine to glutamine change at residue 296. PMID: 23255552
亞細(xì)胞定位：

Golgi apparatus membrane; Single-pass type II membrane protein.
蛋白家族：

Glycosyltransferase 6 family
組織特異性：

Widely expressed. Expressed at higher level in placenta, ovary and peripheral blood leukocyte, whereas it is weakly expressed in liver, thymus, and testis. Expressed in bone marrow erythroid cells.
數(shù)據(jù)庫鏈接：

HGNC: 20460

OMIM: 606074

KEGG: hsa:26301

STRING: 9606.ENSP00000361110

UniGene: Hs.495419