Recombinant Human F-box and leucine-rich protein 22 (FBXL22)

中文名稱：

人FBXL22重組蛋白
貨號：

CSB-YP757543HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人FBXL22重組蛋白
貨號：

CSB-EP757543HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人FBXL22重組蛋白
貨號：

CSB-EP757543HU-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人FBXL22重組蛋白
貨號：

CSB-BP757543HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人FBXL22重組蛋白
貨號：

CSB-MP757543HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

FBXL22
Uniprot No.：

Q6P050
別名：

FBXL22F-box and leucine-rich protein 22
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區(qū)域：

1-247
氨基酸序列

MWPLLTMHIT QLNRECLLHL FSFLDKDSRK SLARTCSQLH DVFEDPALWS LLHFRSLTEL QKDNFLLGPA LRSLSICWHS SRVQVCSIED WLKSAFQRSI CSRHESLVND FLLRVCDRLS AVRSPRRREA PAPSSGTPIA VGPKSPRWGG PDHSEFADLR SGVTGARAAA RRGLGSLRAE RPSETPPAPG VSWGPPPPGA PVVISVKQEE GKQGRTGRRS HRAAPPCGFA RTRVCPPTFP GADAFPQ
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes ubiquitination of sarcomeric proteins alpha-actinin-2 (ACTN2) and filamin-C (FLNC).
基因功能參考文獻：
1. Fbxl22 promotes the proteasome-dependent degradation of sarcomeric proteins and is essential for maintenance of normal contractile function. PMID: 22972877
亞細胞定位：

Cytoplasm, myofibril, sarcomere, Z line.
組織特異性：

Enriched in cardiac muscle.
數(shù)據(jù)庫鏈接：

HGNC: 27537

OMIM: 609088

KEGG: hsa:283807

UniGene: Hs.631163