Recombinant Human Dual specificity protein phosphatase 8 (DUSP8), partial

中文名稱：

人DUSP8重組蛋白
貨號(hào)：

CSB-YP614399HU1
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人DUSP8重組蛋白
貨號(hào)：

CSB-EP614399HU1
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人DUSP8重組蛋白
貨號(hào)：

CSB-EP614399HU1-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人DUSP8重組蛋白
貨號(hào)：

CSB-BP614399HU1
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人DUSP8重組蛋白
貨號(hào)：

CSB-MP614399HU1
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

DUSP8
Uniprot No.：

Q13202
別名：

C11orf81; Chromosome 11 open reading frame 81 ; Deubiquitinating enzyme 8; Dual Specificity Phosphatase 8; Dual specificity phosphatase M3/6; Dual specificity protein phosphatase 8; Dual specificity protein phosphatase hVH 5; Dual specificity protein phosphatase hVH-5; DUS8; DUS8_HUMAN; DUSP8; EC 3.1.3.16; EC 3.1.3.48; FLJ42476 ; FLJ42958; H1 phosphatase vaccinia virus homolog; H1 phosphatase; vaccinia virus; homolog of; HB5; hUBPy; HVH5; HVH8; M3/6; mouse; homolog of; Neuronal tyrosine threonine phosphatase 1; Serine/threonine specific protein phosphatase ; Ubiquitin carboxyl terminal hydrolase 8; Ubiquitin specific processing protease 8; Ubiquitin thiolesterase 8; VH5
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Has phosphatase activity with synthetic phosphatase substrates and negatively regulates mitogen-activated protein kinase activity, presumably by catalysing their dephosphorylation. Expected to display protein phosphatase activity toward phosphotyrosine, phosphoserine and phosphothreonine residues.
基因功能參考文獻(xiàn)：
1. The phosphorylation of the M3/6 phosphatase by JNK in response to stress stimuli results in attenuation of phosphatase activity and acceleration of JNK activation. PMID: 22100391
2. DUSP8 is genetically linked to alcohol dependence and was found on chromosome 11p15.5 PMID: 13129832
3. Because this variant of hVH-5 lacked intronic sequences in its genomic structure, we suggest it might be a processed pseudogene of hVH-5. PMID: 15899389
亞細(xì)胞定位：

Cytoplasm. Nucleus.
蛋白家族：

Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
組織特異性：

Abundant in brain, heart and skeletal muscle.
數(shù)據(jù)庫鏈接：

HGNC: 3074

OMIM: 602038

KEGG: hsa:1850

STRING: 9606.ENSP00000329539

UniGene: Hs.41688