Recombinant Human Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (ARAP2), partial

中文名稱：

Recombinant Human Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2(ARAP2) ,partial
貨號：

CSB-YP855511HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2(ARAP2) ,partial
貨號：

CSB-EP855511HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2(ARAP2) ,partial
貨號：

CSB-EP855511HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2(ARAP2) ,partial
貨號：

CSB-BP855511HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2(ARAP2) ,partial
貨號：

CSB-MP855511HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ARAP2
Uniprot No.：

Q8WZ64
別名：

ARAP2; CENTD1; KIAA0580Arf-GAP with Rho-GAP domain; ANK repeat and PH domain-containing protein 2; Centaurin-delta-1; Cnt-d1; Protein PARX
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency.
基因功能參考文獻：
1. ACAP1 and ARAP2 each colocalize with Arf6 but they did not colocalize with each other and have opposing effects on focal adhesions. PMID: 25225293
2. ARAP2 signals through Arf6 and Rac1 to control focal adhesion morphology PMID: 23295182
3. Our findings indicate that ARAP2 promotes InlB-mediated entry of Listeria monocytogenes in part, by antagonizing the host GTPase Arf6. PMID: 20823205
4. ARAP2 is an Arf6GAP that functions downstream of RhoA to regulate focal adhesion dynamics. PMID: 17077126
亞細胞定位：

Cytoplasm.
組織特異性：

Detected in brain, thymus, lymph node, thyroid, spinal cord, trachea, heart, skeletal muscle, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes.
數據庫鏈接：

HGNC: 16924

OMIM: 606645

KEGG: hsa:116984

STRING: 9606.ENSP00000302895

UniGene: Hs.479451