Recombinant Human Acyl-coenzyme A synthetase ACSM3, mitochondrial (ACSM3)

中文名稱：

Recombinant Human Acyl-coenzyme A synthetase ACSM3, mitochondrial(ACSM3)
貨號：

CSB-YP709601HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human Acyl-coenzyme A synthetase ACSM3, mitochondrial(ACSM3)
貨號：

CSB-EP709601HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human Acyl-coenzyme A synthetase ACSM3, mitochondrial(ACSM3)
貨號：

CSB-EP709601HU-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human Acyl-coenzyme A synthetase ACSM3, mitochondrial(ACSM3)
貨號：

CSB-BP709601HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human Acyl-coenzyme A synthetase ACSM3, mitochondrial(ACSM3)
貨號：

CSB-MP709601HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

ACSM3
Uniprot No.：

Q53FZ2
別名：

ACSM3; ACSM3_HUMAN; Acyl CoA synthetase medium chain family member 3; Acyl-CoA synthetase medium-chain family member 3; Acyl-coenzyme A synthetase ACSM3; Acyl-coenzyme A synthetase ACSM3; mitochondrial; Butyrate CoA ligase 3; Butyrate--CoA ligase 3; Butyryl coenzyme A synthetase 3; Butyryl-coenzyme A synthetase 3; Middle chain acyl CoA synthetase 3; Middle-chain acyl-CoA synthetase 3; mitochondrial; Protein SA homolog; SA (rat hypertension associated) homolog; SA; SA hypertension associated homolog; SA; rat; homolog of; SAH
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length of Mature Protein
表達(dá)區(qū)域：

28-586
氨基酸序列

LHK DNRTATPQNF SNYESMKQDF KLGIPEYFNF AKDVLDQWTD KEKAGKKPSN PAFWWINRNG EEMRWSFEEL GSLSRKFANI LSEACSLQRG DRVILILPRV PEWWLANVAC LRTGTVLIPG TTQLTQKDIL YRLQSSKANC IITNDVLAPA VDAVASKCEN LHSKLIVSEN SREGWGNLKE LMKHASDSHT CVKTKHNEIM AIFFTSGTSG YPKMTAHTHS SFGLGLSVNG RFWLDLTPSD VMWNTSDTGW AKSAWSSVFS PWIQGACVFT HHLPRFEPTS ILQTLSKYPI TVFCSAPTVY RMLVQNDITS YKFKSLKHCV SAGEPITPDV TEKWRNKTGL DIYEGYGQTE TVLICGNFKG MKIKPGSMGK PSPAFDVKIV DVNGNVLPPG QEGDIGIQVL PNRPFGLFTH YVDNPSKTAS TLRGNFYITG DRGYMDKDGY FWFVARADDV ILSSGYRIGP FEVENALNEH PSVAESAVVS SPDPIRGEVV KAFVVLNPDY KSHDQEQLIK EIQEHVKKTT APYKYPRKVE FIQELPKTIS GKTKRNELRK KEWKTI
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

功能：

Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism. Capable of activating medium-chain fatty acids with a preference for isobutyrate among fatty acids with 2-6 carbon atoms.
基因功能參考文獻(xiàn)：
1. Our data provide evidence for a differential expression and regulation of the ACSM3 gene in hepatocellular carcinoma PMID: 28390038
2. Reduced ACSM3 is associated with impaired butyrate oxidation in ulcerative colitis. PMID: 21987487
3. SA gene polymorphism may be associated with the renal prognosis of immunoglobulin A nephropathy through its effect on blood pressure. Sensitivity to this gene polymorphism increases in patients with renal injury. PMID: 12484505
4. variation in SAH has a role in predisposition to overweight in hypertensives. PMID: 14567496
5. confirms recent evidence that the SAH locus is associated with obesity-related hypertension PMID: 17278971
6. family-based analyses of SA hypertension-associated homolog (SAH) gene variants did not reveal population stratification supporting an association of hypertension and gene variants PMID: 18192838
7. We conclude that, in spite of its renal expression,1-3 the human SAH gene is unlikely to have an important role in renal sodium handling. PMID: 18519841
8. SA hypertension-associated homolog(SAH) gene polymorphisms are associated with non-high-density lipoprotein cholesterol in postmenopausal women PMID: 19108963
9. left ventricular mass index and mean wall thickness , two phenotypes that are jointly influenced by blood pressure and obesity, might be related to variation in the human SAH gene PMID: 19262474
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亞細(xì)胞定位：

Mitochondrion. Mitochondrion matrix.
蛋白家族：

ATP-dependent AMP-binding enzyme family
數(shù)據(jù)庫鏈接：

HGNC: 10522

OMIM: 145505

KEGG: hsa:6296

STRING: 9606.ENSP00000289416

UniGene: Hs.706754