Recombinant Human 60S ribosomal protein L15 (RPL15)

中文名稱：

人RPL15重組蛋白
品名簡稱：

Recombinant Human RPL15 protein
貨號：

CSB-RP024354h
說明書：

MSDS Datasheet
規(guī)格：

￥1344
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

Greater than 90% as determined by SDS-PAGE.
基因名：

RPL15
Uniprot No.：

P61313
別名：

60S ribosomal protein L15; EC45; FLJ26304; ribosomal protein L15 ; RL15_HUMAN; RPL10; RPL15; RPLY10 ; RPYL10
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length of Mature Protein
來源：

E.coli
分子量：

51.0kDa
表達區(qū)域：

2-204aa
氨基酸序列

GAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標(biāo)簽：

N-terminal GST-tagged
產(chǎn)品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

基因功能參考文獻：
1. Aurora kinase inhibitor danusertib negatively regulated AURKB/p70S6K/RPL15 axis with the involvement of PI3K/Akt/mTOR, AMPK, and p38 MAPK signaling pathways, leading to the induction of apoptosis and autophagy in human leukemia cells. PMID: 27612557
2. Downregulation of RPL15 is associated with tumor progression in pancreatic ductal adenocarcinoma. PMID: 26498693
3. These data identify RPL15 as a new gene involved in Diamond-Blackfan anemia. PMID: 23812780
4. ISG56 interacts with ribosomal protein L15 in gastric cancer cells. PMID: 21612406
5. RPL15 gene expression is decreased in both classic and follicular variants of papillary thyroid carcinoma. PMID: 21509594
6. RPL15 promotes cell proliferation in gastric neoplasms PMID: 16608517
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相關(guān)疾病：

Diamond-Blackfan anemia 12 (DBA12)
亞細(xì)胞定位：

Membrane; Lipid-anchor.
蛋白家族：

Eukaryotic ribosomal protein eL15 family
數(shù)據(jù)庫鏈接：

HGNC: 10306

OMIM: 604174

KEGG: hsa:6138

STRING: 9606.ENSP00000309334

UniGene: Hs.381219