Recombinant Homeobox protein mab-5 (mab-5)

中文名稱：

秀麗隱桿線蟲mab-5重組蛋白
貨號：

CSB-YP319860CXY
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

秀麗隱桿線蟲mab-5重組蛋白
貨號：

CSB-EP319860CXY
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

秀麗隱桿線蟲mab-5重組蛋白
貨號：

CSB-EP319860CXY-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

秀麗隱桿線蟲mab-5重組蛋白
貨號：

CSB-BP319860CXY
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

秀麗隱桿線蟲mab-5重組蛋白
貨號：

CSB-MP319860CXY
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

mab-5
Uniprot No.：

P10038
別名：

mab-5; C08C3.3Homeobox protein mab-5; Protein male abnormal 5
種屬：

Caenorhabditis elegans
蛋白長度：

full length protein
表達區域：

1-200
氨基酸序列

MSMYPGWTGD DSYWAGAGTT ASSQSASSGT SASASSSAAA AAAANNLKTY ELYNHTYMNN MKHMLAAGWM DNSSNPFAYN PLQATSANFG ETRTSMPAIS QPVFPWMKMG GAKGGESKRT RQTYSRSQTL ELEKEFHYHK YLTRKRRQEI SETLHLTERQ VKIWFQNRRM KHKKEAKGEG GSNESDEESN QDEQNEQHSS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Transcription factor that binds to the promoter region of the transcription factor lin-39 to repress its expression in Q neuroblasts and thereby direct left Q neuroblast (QL) daughter cell migration. During postembryonic development, required for posterior-specific pattern formation. Within the posterior body region, controls epidermal, neuronal, and mesodermal cell differentiation.
基因功能參考文獻：
1. EGL-20 mediates an acute inhibition of anterior migration independently of BAR-1 and MAB-5, and a later, possible transcriptional response mediated by BAR-1 and MAB-5. PMID: 26863303
2. Genes regulated by MAB-5 were enriched for those encoding secreted and transmembrane molecules that affect extracellular matrix PMID: 23642123
3. Data show wild-type mab-5 function is necessary for normal P(9-11).p fate. PMID: 20478294
4. role of MAB-5 during ray formation; results suggest functional specificity to be conferred by the N-terminal arm and helix I, but not helix II of the homeodomain PMID: 12538523
5. mab-5 expression was studied in neuroblast lineage in this nematode. PMID: 12930745
6. In the P11 lineage, a complex between MAB-5 and the Pbx homolog CEH-20 directly regulates transcription of the BH3 domain gene egl-1 to initiate programmed cell death. PMID: 16421192
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亞細胞定位：

Nucleus.
蛋白家族：

Antp homeobox family
組織特異性：

Expressed asymmetrically in the QL neuroblast.
數據庫鏈接：

KEGG: cel:CELE_C08C3.3

STRING: 6239.C08C3.3

UniGene: Cel.18387