Recombinant Escherichia coli Multidrug resistance protein MdtK (mdtK), partial

中文名稱：

大腸桿菌mdtK重組蛋白
貨號：

CSB-YP336284ENV
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大腸桿菌mdtK重組蛋白
貨號：

CSB-EP336284ENV
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大腸桿菌mdtK重組蛋白
貨號：

CSB-EP336284ENV-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大腸桿菌mdtK重組蛋白
貨號：

CSB-BP336284ENV
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大腸桿菌mdtK重組蛋白
貨號：

CSB-MP336284ENV
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

mdtK
Uniprot No.：

P37340
別名：

mdtK; norE; norM; ydhE; b1663; JW1655Multidrug resistance protein MdtK; Multidrug-efflux transporter
種屬：

Escherichia coli (strain K12)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Multidrug efflux pump that probably functions as a Na(+)/drug antiporter. Confers resistance to many drugs such as fluoroquinolones (norfloxacin, ciprofloxacin, enoxacin) and tetraphenylphosphonium ion (TPP). Also to deoxycholate, doxorubicin, trimethoprim, chloramphenicol, fosfomycin, ethidium bromide and benzalkonium. Also able to export peptides; when overexpressed, allows cells deleted for multiple peptidases (pepA, pepB, pepD and pepN) to grow in the presence of dipeptides Ala-Gln or Gly-Tyr which otherwise inhibit growth. Cells overexpressing this protein have decreased intracellular levels of Ala-Gln dipeptide, and in a system that produces the Ala-Gln dipeptide overproduction of this protein increases export of the dipeptide.
基因功能參考文獻：
1. NorM protects the cell from reactive oxygen specie when the 8-oxoguanine-repair-deficient mutant cannot cope with the DNA damage. PMID: 20463878
2. A putative multidrug efflux protein (NorM) from V. parahaemolyticus and its homologue YdhE (NorM) from E. coli were identified. PMID: 9661020
3. In this study, Delta norE (norM) mutants grow to higher cell density in stationary phase than wild type. Overproduction of NorE (NorM) pump caused cells to reach lower density. NorE (NorM) might export signals for cell-cell communication. PMID: 16467145
亞細胞定位：

Cell inner membrane; Multi-pass membrane protein.
蛋白家族：

Multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family, MdtK subfamily
數據庫鏈接：

KEGG: ecj:JW1655

STRING: 316385.ECDH10B_1797