Recombinant Drosophila melanogaster Transient receptor potential protein (trp), partial

中文名稱：

黑腹果蠅trp重組蛋白
貨號：

CSB-YP325665DLU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

黑腹果蠅trp重組蛋白
貨號：

CSB-EP325665DLU
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

黑腹果蠅trp重組蛋白
貨號：

CSB-EP325665DLU-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

黑腹果蠅trp重組蛋白
貨號：

CSB-BP325665DLU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

黑腹果蠅trp重組蛋白
貨號：

CSB-MP325665DLU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

trp
Uniprot No.：

P19334
別名：

trp; CG7875; Transient receptor potential protein
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

功能：

A light-sensitive calcium channel that is required for inositide-mediated Ca(2+) entry in the retina during phospholipase C (PLC)-mediated phototransduction. Ca(2+) influx may then feed back and inhibit PLC, thereby facilitating phosphatidylinositol 4,5 bisphosphate (PIP2) recycling. Trp and trpl act together in the light response, though it is unclear whether as heteromultimers or as distinct units, and are activated by fatty acids and metabolic stress. Also required for olfactory adaptation and may be involved in olfactory system development.
基因功能參考文獻(xiàn)：
1. Calmodulin binding could induce secondary structure changes in Drosophila TRP C-terminus.TRP 783-862 is a novel calmodulin binding site PMID: 29730291
2. results indicate that properties of the light-activated channels together with the dynamic light-dependent process of TRP phosphorylation at the S936 site determine response kinetics PMID: 28762890
3. TRP de-phosphorylation affects the detection limit of oscillating light in photoreceptor cells. PMID: 28314815
4. Data show that phosphorylation of most ransient receptor potential (TRP) ion channel sites depends on the phototransduction cascade and the activity of the TRP. PMID: 24040070
5. These results indicate that the Pain TRP channels in the MBs and IPCs control neuronal plasticity that is required for the formation of a certain type of long-lasting associative memory in Drosophila. PMID: 23247253
6. members of the TRP family are "special assignment" channels, which are recruited to diverse signaling pathways. PMID: 11917094
7. Single amino acid change in the fifth transmembrane segment of the TRP Ca2+ channel causes massive degeneration of photoreceptors. PMID: 12107168
8. Paper briefly overviews current knowledge of TRP and its mammalian homologues as non-voltage-gated Ca2+ channels that are constitutively active or gated by a multitude of stimuli; thus TRPs may play divergent roles in cell pathophysiology. PMID: 12719655
9. Data show that a substantial reduction of the TRP channel protein by RNA interference completely rescues neuronal degeneration and significantly improves the light-elicited responses of the eye. PMID: 15342118
10. TRP has independent channel and scaffolding roles PMID: 16301334
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亞細(xì)胞定位：

Cell membrane; Multi-pass membrane protein. Note=Localized on plasma membrane loops found at the base of the rhabdomere, in close proximity to the calcium stores.
蛋白家族：

Transient receptor (TC 1.A.4) family, STrpC subfamily
組織特異性：

Expressed predominantly in the rhabdomeres of photoreceptor cells. Expressed in the third antennal segment and in the olfactory segment at approximately 70 hours after puparium formation during antennal development.
數(shù)據(jù)庫鏈接：

KEGG: dme:Dmel_CG7875

STRING: 7227.FBpp0084879

UniGene: Dm.21694