Recombinant Drosophila melanogaster Thioredoxin-1 (dhd)

中文名稱：

黑腹果蠅dhd重組蛋白
貨號：

CSB-YP342129DLU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

黑腹果蠅dhd重組蛋白
貨號：

CSB-EP342129DLU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

黑腹果蠅dhd重組蛋白
貨號：

CSB-EP342129DLU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

黑腹果蠅dhd重組蛋白
貨號：

CSB-BP342129DLU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

黑腹果蠅dhd重組蛋白
貨號：

CSB-MP342129DLU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

dhd
Uniprot No.：

P47938
別名：

dhd; Trx-1; CG4193; Thioredoxin-1; DmTrx-1; Protein deadhead
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

full length protein
表達區域：

1-107
氨基酸序列

MASVRTMNDY HKRIEAADDK LIVLDFYATW CGPCKEMEST VKSLARKYSS KAVVLKIDVD KFEELTERYK VRSMPTFVFL RQNRRLASFA GADEHKLTNM MAKLVKA
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. Required for female meiosis and early embryonic development.
基因功能參考文獻：
1. This study demonstrates that DHD localizes to the sperm nucleus to reduce its disulfide targets and is then rapidly degraded after fertilization. PMID: 27876811
2. thioredoxin DHD plays a critical role in early development to facilitate the switch from protamine-based sperm chromatin structures to the somatic nucleosomal chromatin. PMID: 28031247
3. evidence for distinct biological function of Trx-1 PMID: 11877442
4. dimer dissociation constants K(d) were found to be 2.2mM for reduced DmTrx and above 10mM for oxidized DmTrx as well as for the protein in the presence of reduced glutathione PMID: 15644209
亞細胞定位：

Nucleus.
蛋白家族：

Thioredoxin family
組織特異性：

Ovary specific. Expressed present in the nurse cells from stage 9 of ovary development and is transported into the oocyte. Expressed throughout oogenesis.
數據庫鏈接：

KEGG: dme:Dmel_CG4193

STRING: 7227.FBpp0070717

UniGene: Dm.2955