Recombinant Drosophila melanogaster TATA-box-binding protein (Tbp)

中文名稱：

黑腹果蠅Tbp重組蛋白
貨號：

CSB-YP023239DLU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

黑腹果蠅Tbp重組蛋白
貨號：

CSB-EP023239DLU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

黑腹果蠅Tbp重組蛋白
貨號：

CSB-EP023239DLU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

黑腹果蠅Tbp重組蛋白
貨號：

CSB-BP023239DLU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

黑腹果蠅Tbp重組蛋白
貨號：

CSB-MP023239DLU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Tbp
Uniprot No.：

P20227
別名：

Tbp; BTF1; TFIID; CG9874; TATA-box-binding protein; TATA sequence-binding protein; TATA-binding factor; TATA-box factor; Transcription initiation factor TFIID TBP subunit
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

full length protein
表達區域：

1-353
氨基酸序列

MDQMLSPNFS IPSIGTPLHQ MEADQQIVAN PVYHPPAVSQ PDSLMPAPGS SSVQHQQQQQ QSDASGGSGL FGHEPSLPLA HKQMQSYQPS ASYQQQQQQQ QLQSQAPGGG GSTPQSMMQP QTPQSMMAHM MPMSERSVGG SGAGGGGDAL SNIHQTMGPS TPMTPATPGS ADPGIVPQLQ NIVSTVNLCC KLDLKKIALH ARNAEYNPKR FAAVIMRIRE PRTTALIFSS GKMVCTGAKS EDDSRLAARK YARIIQKLGF PAKFLDFKIQ NMVGSCDVKF PIRLEGLVLT HCNFSSYEPE LFPGLIYRMV RPRIVLLIFV SGKVVLTGAK VRQEIYDAFD KIFPILKKFK KQS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.
基因功能參考文獻：
1. TFIID has two disctinct modes of transcription initiation, de novo initiation and reinitiation, as revealed by the inhibitory effect of TFIID-bound tin compounds on the de novo initiation, but not on the reinitiation. PMID: 26314865
2. Deactivation of TBP contributes to SCA17 pathogenesis. PMID: 25104854
3. Aptamers generated by both selections were able to bind specifically to TBP, but the two groups showed characteristics which were clearly different in terms of their capability to compete with TATA-DNA. PMID: 23924740
4. Tbp targets core histone transcription. PMID: 17978101
亞細胞定位：

Nucleus.
蛋白家族：

TBP family
數據庫鏈接：

KEGG: dme:Dmel_CG9874

STRING: 7227.FBpp0071596

UniGene: Dm.4490