Recombinant Drosophila melanogaster Serine-arginine protein 55 (B52)

中文名稱：

Recombinant Drosophila melanogaster Serine-arginine protein 55(B52)
貨號：

CSB-YP328642DLU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Drosophila melanogaster Serine-arginine protein 55(B52)
貨號：

CSB-EP328642DLU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Drosophila melanogaster Serine-arginine protein 55(B52)
貨號：

CSB-EP328642DLU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Drosophila melanogaster Serine-arginine protein 55(B52)
貨號：

CSB-BP328642DLU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Drosophila melanogaster Serine-arginine protein 55(B52)
貨號：

CSB-MP328642DLU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

B52
Uniprot No.：

P26686
別名：

B52; E(Dfd); RS55; SR55; CG10851; Serine-arginine protein 55; SRP55; 52 kDa bracketing protein; B52 protein; Protein enhancer of deformed
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

Full Length of Mature Protein
表達區域：

2-376
氨基酸序列

VGSRVYVGG LPYGVRERDL ERFFKGYGRT RDILIKNGYG FVEFEDYRDA DDAVYELNGK ELLGERVVVE PARGTARGSN RDRYDDRYGG RRGGGGGRYN EKNKNSRSSS RYGPPLRTEY RLIVENLSSR VSWQDLKDYM RQAGEVTYAD AHKQRRNEGV VEFASLSDMK TAIEKLDDTE LNGRRIHLVE DRRGGRSGGG GGSGRGRSRS SSSRSRSRSR RRSRSRRSSH SRSKSRSRSK SRGGRSKSKS PVKSRSRSRS RSNKSRDVSK SKSKSHSRTR SRSPKRERDS RSRSRSVSKR ESRSRSRSKS IHRDSRSRPP TVSFKSSFYK FTTMPFFCSD RSASAENKSR SRSRSRSASP KNGNASPDRN NESMDD
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Essential for development. May have a critical role in splicing or in controlling alternative splice site use of at least some pre-mRNA in vivo. Not required for all splicing. May play a general role in the condensation or decondensation of chromatin.
基因功能參考文獻：
1. Loss of B52 increases growth of axon branches. B52 function is also required for Choline acetyltransferase (ChAT ) splicing. PMID: 27725692
2. B52 overexpression increases cell growth, upregulates myc transcription, and gives rise to flies lacking thoracic bristles. PMID: 25680814
3. B52/SRp55 generates 2 isoforms of eyeless differing by an alternative exon encoding a 60-AA insert at the beginning of the paired domain. In normal eye development B52/SRp55 controls eye organogenesis & size by regulating eyeless alternative splicing. PMID: 17327915
4. The SR proteins dASF/SF2 and B52 caused defects in ommatidia structure, and B52 impaired normal axonal projections of photoreceptors and neurogenesis in visual ganglia. PMID: 17283056
亞細胞定位：

Nucleus. Note=Associated with boundaries of transcriptionally active chromatin.
蛋白家族：

Splicing factor SR family
數據庫鏈接：

KEGG: dme:Dmel_CG10851

UniGene: Dm.2188