Recombinant Drosophila melanogaster Histone deacetylase complex subunit SAP18 (Bin1)

中文名稱：

Recombinant Drosophila melanogaster Histone deacetylase complex subunit SAP18(Bin1)
貨號：

CSB-YP895601DLU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Drosophila melanogaster Histone deacetylase complex subunit SAP18(Bin1)
貨號：

CSB-EP895601DLU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Drosophila melanogaster Histone deacetylase complex subunit SAP18(Bin1)
貨號：

CSB-EP895601DLU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Drosophila melanogaster Histone deacetylase complex subunit SAP18(Bin1)
貨號：

CSB-BP895601DLU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Drosophila melanogaster Histone deacetylase complex subunit SAP18(Bin1)
貨號：

CSB-MP895601DLU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Bin1
Uniprot No.：

Q9VEX9
別名：

Bin1; SAP18; CG6046; Histone deacetylase complex subunit SAP18; 18 kDa Sin3-associated polypeptide; Bicoid-interacting protein 1; dSAP18
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

full length protein
表達區域：

1-150
氨基酸序列

MANVESMIVE EKTQVKQIDR EKTCPMLLRV FCSTGRHHSV SEYMFGNVPT NELQIYTWQD ATLHELTSLV RDVNPDTRKK GTYFDFAVVY PNFRSNHFQM REIGVTCTGQ KGIDDNKTLA QAKFSIGDFL DISITPPNRL PPTARRQRPY
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in the tethering of the SIN3 complex to core histone proteins. Interacts with bicoid (bcd) to repress transcription of bicoid target genes in the anterior tip of the embryo; a process known as retraction. Interacts with Trl and binds to Polycomb response elements at the bithorax complex. May contribute to the regulation of other homeotic gene expressions.
基因功能參考文獻：
1. The findings reveal the ability of Bin1 to modify actin dynamics and provide a possible mechanistic connection between Bin1 and tau-induced pathobiological changes of the actin cytoskeleton. PMID: 28893863
2. dSAP18 is a key player in transcriptional responses to stress. PMID: 21146528
3. removal of maternal sap18 results in embryos that are missing labrally derived parts of the cephalopharyngeal skeleton PMID: 15649476
4. Drosophila dSAP18 protein is a nuclear protein that associates with chromosomes and the nuclear matrix and interacts with pinin involved in RNA splicing. PMID: 16823614
亞細胞定位：

Nucleus. Cytoplasm.
蛋白家族：

SAP18 family
數據庫鏈接：

KEGG: dme:Dmel_CG6046

STRING: 7227.FBpp0082731

UniGene: Dm.20197