Recombinant Drosophila melanogaster Histone H3 (His3)

中文名稱：

黑腹果蠅His3;重組蛋白
貨號：

CSB-YP365735DLU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

黑腹果蠅His3;重組蛋白
貨號：

CSB-EP365735DLU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

黑腹果蠅His3;重組蛋白
貨號：

CSB-EP365735DLU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

黑腹果蠅His3;重組蛋白
貨號：

CSB-BP365735DLU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

黑腹果蠅His3;重組蛋白
貨號：

CSB-MP365735DLU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

His3;
Uniprot No.：

P02299
別名：

His3;; His3:CG31613; CG31613;; His3:CG33803; CG33803;; His3:CG33806; CG33806;; His3:CG33809; CG33809;; His3:CG33812; CG33812;; His3:CG33815; CG33815;; His3:CG33818; CG33818;; His3:CG33821; CG33821;; His3:CG33824; CG33824;; His3:CG33827; CG33827;; His3:CG33830; CG33830;; His3:CG33833; CG33833;; His3:CG33836; CG33836;; His3:CG33839; CG33839;; His3:CG33842; CG33842;; His3:CG33845; CG33845;; His3:CG33848; CG33848;; His3:CG33851; CG33851;; His3:CG33854; CG33854;; His3:CG33857; CG33857;; His3:CG33860; CG33860;; His3:CG33863; CG33863;; His3:CG33866; CG33866; Histone H3
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

Full Length of Mature Protein
表達區域：

2-136
氨基酸序列

ARTKQTARK STGGKAPRKQ LATKAARKSA PATGGVKKPH RYRPGTVALR EIRRYQKSTE LLIRKLPFQR LVREIAQDFK TDLRFQSSAV MALQEASEAY LVGLFEDTNL CAIHAKRVTI MPKDIQLARR IRGERA
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
基因功能參考文獻：
1. Acetylation of histone H3 lysine 23 is localized to promoters and correlates with endogenous ecdysone induced gene activation. PMID: 22808194
2. In Su(var)3-9 null mutants, H3-K9 methylation at chromocentre heterochromatin is strongly reduced, indicating that SU(VAR)3-9 is the major heterochromatin-specific HMTase in Drosophila. PMID: 11867540
3. Phosphorylation of H3 is linked to transcription and can be modulated by the structure of the promoter. PMID: 12514098
亞細胞定位：

Nucleus. Chromosome.
蛋白家族：

Histone H3 family
數據庫鏈接：

KEGG: dme:Dmel_CG31613

STRING: 7227.FBpp0091112