Recombinant Danio rerio Plexin A3 (plxna3), partial

中文名稱：

斑馬魚plxna3重組蛋白
貨號：

CSB-YP018219DIL
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

斑馬魚plxna3重組蛋白
貨號：

CSB-EP018219DIL
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

斑馬魚plxna3重組蛋白
貨號：

CSB-EP018219DIL-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

斑馬魚plxna3重組蛋白
貨號：

CSB-BP018219DIL
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

斑馬魚plxna3重組蛋白
貨號：

CSB-MP018219DIL
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

plxna3
Uniprot No.：

B0S5N4
別名：

plxna3; si:dkey-7i23.3; Plexin A3
種屬：

Danio rerio (Zebrafish) (Brachydanio rerio)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Coreceptor for class 3 semaphorins. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
基因功能參考文獻：
1. \Homodimerization of PlxnA3 caused by mutation M1281L remains in the presence of ligand semaphorin 3F and co-receptor neuropilin-2a. PMID: 25565389
2. Data show that null mutants of the guidance receptor plexin A3 display motor axon branching defects. PMID: 23349787
3. in vivo demonstration of the intersection of spontaneous electrical activity with the PlexinA3 guidance molecule receptor in regulation of axon pathfinding PMID: 23302694
4. study shows plexinA3 is a crucial receptor for axon guidance cues in primary motor neurons PMID: 17475806
5. Plexin A3 plays an additional role in motor axonal morphogenesis. PMID: 17699603
6. Plxna3 acts with its ligand Sema3a1 for fasciculation and correct target selection of the Vp and VII motor axons. PMID: 17699608
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亞細胞定位：

Cell membrane; Single-pass type I membrane protein.
蛋白家族：

Plexin family
組織特異性：

Detected in primary motor neurons in the embryonic nervous system.
數(shù)據(jù)庫鏈接：

KEGG: dre:567422

STRING: 7955.ENSDARP00000043999

UniGene: Dr.80739