Recombinant Danio rerio Malcavernin (ccm2)

中文名稱：

Recombinant Danio rerio Malcavernin(ccm2)
貨號：

CSB-YP738589DIL
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Danio rerio Malcavernin(ccm2)
貨號：

CSB-EP738589DIL
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Danio rerio Malcavernin(ccm2)
貨號：

CSB-EP738589DIL-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Danio rerio Malcavernin(ccm2)
貨號：

CSB-BP738589DIL
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Danio rerio Malcavernin(ccm2)
貨號：

CSB-MP738589DIL
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ccm2
Uniprot No.：

Q6DRP4
別名：

ccm2; vtn; Cerebral cavernous malformations protein 2 homolog; Malcavernin; Valentine
種屬：

Danio rerio (Zebrafish) (Brachydanio rerio)
蛋白長度：

full length protein
表達區域：

1-455
氨基酸序列

MEEDVKKVKK PGIVSPFKRV FLKGEKGRDK KALEKSTERR ALHTFSLSLP DHRIDPDILL NDYIEKEVKY LGQLTSVPGY LNPSSRTEVL QLIDNARKSH QLAGQLTSEQ DAVVSLSAYN VKLVWRDGED IILRVPIHDI AAVSYIRDDS LHLVVLKTAQ EPGGSPCHST EMSKSPTLSS LSESGAVLVE VCCLLVLAVD NKAAAEELCL LLSQVFQIVY TESTIDFLDR AIFDGATTPT RHLSIYSEDS SSKVDVKDVF EAEASTFSFQ SSLEAGHSSS PSPTSAPASP QTKTASESEL STTAAELLQD YMTTLRTKLS SKEIQQFATL LHEYRNGASI HEFCINLRQL YGDSRKFLLL GLRPFIPEKD SQHFENFLET IGVKDGRGII TDSFGRYKRT TSSASDSTTN GNGAAGGSDE GTATSEGDEW DRMISDISND IEALGSSMDQ DGVPS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions. May also function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock.
基因功能參考文獻：
1. These findings suggest that CCM2L and CCM2 cooperate to regulate the activity of MEKK3. PMID: 26540726
亞細胞定位：

Cytoplasm.
蛋白家族：

CCM2 family
數據庫鏈接：

KEGG: dre:436586

STRING: 7955.ENSDARP00000022543

UniGene: Dr.107920