Recombinant Danio rerio Insulin gene enhancer protein isl-2a (isl2a)

中文名稱：

斑馬魚isl2a重組蛋白
貨號：

CSB-YP346859DIL
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

斑馬魚isl2a重組蛋白
貨號：

CSB-EP346859DIL
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

斑馬魚isl2a重組蛋白
貨號：

CSB-EP346859DIL-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

斑馬魚isl2a重組蛋白
貨號：

CSB-BP346859DIL
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

斑馬魚isl2a重組蛋白
貨號：

CSB-MP346859DIL
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

isl2a
Uniprot No.：

P53406
別名：

isl2a; isl-2; isl2; Insulin gene enhancer protein isl-2a; Islet-2A; Insulin gene enhancer protein isl-2; Islet-2
種屬：

Danio rerio (Zebrafish) (Brachydanio rerio)
蛋白長度：

full length protein
表達區域：

1-359
氨基酸序列

MVDILPHPSF LGDMGDHSKK KSGIAMCVGC GSQIHDQYIL RVSPDLEWHA ACLKCAECSQ YLDETCTCFV RDGKTYCKRD YVRLFGIKCA KCNIGFCSSD LVMRARDNVY HMECFRCSVC SRHLLPGDEF SLRDEELLCR ADHGLLMERA SAGSPISPGN IHSSRPLHIP EPVPVRQPPH RNHVHKQSEK TTRVRTVLNE KQLHTLRTCY NANPRPDALM KEQLVEMTGL SPRVIRVWFQ NKRCKDKKKS ILMKQLQQQQ HNDKTNLQGL TGTPLVAGSP IRHDTTVQGN PVEVQTYQPP WKALSEFALQ SDLDQPAFQQ LVSFSESGSL GNSSGSDVTS LSSQLPDTPN SMVPSPVET
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Binds to one of the cis-acting domain of the insulin gene enhancer. May be involved in subtype specialization of primary motoneurons.
基因功能參考文獻：
1. Isl2a is expressed in the lateral posterior mesoderm prior to angioblast migration. Isl2a-deficient angioblasts show disorganized migration to the midline to form axial vessels. Its expression is negatively regulated by Notch activity. It positively regulates flt4, a VEGF-C receptor repressed by Notch during angiogenesis. Isl2a may be an intermediate between Notch signaling and genetic programs controlling angioblasts. PMID: 27126199
2. Prdm14 regulates caudal rimary axon outgrowth through activation of islet2 expression. PMID: 23136389
3. Results show that PlexinA4, a transmembrane protein known to be a co-receptor for class III semaphorins, acts downstream of Islet2 to promote branching of the peripheral axons of the primary sensory neurons. PMID: 15229183
亞細胞定位：

Nucleus.
數據庫鏈接：

KEGG: dre:30157

STRING: 7955.ENSDARP00000020636

UniGene: Dr.281