Recombinant Chicken Mothers against decapentaplegic homolog 6 (SMAD6)

中文名稱：

雞SMAD6重組蛋白
貨號：

CSB-YP892952CH
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

雞SMAD6重組蛋白
貨號：

CSB-EP892952CH
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

雞SMAD6重組蛋白
貨號：

CSB-EP892952CH-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

雞SMAD6重組蛋白
貨號：

CSB-BP892952CH
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

雞SMAD6重組蛋白
貨號：

CSB-MP892952CH
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

SMAD6
Uniprot No.：

Q9W734
別名：

SMAD6; MADH6; Mothers against decapentaplegic homolog 6; MAD homolog 6; Mothers against DPP homolog 6; SMAD family member 6; SMAD 6; Smad6
種屬：

Gallus gallus (Chicken)
蛋白長度：

full length protein
表達區域：

1-431
氨基酸序列

MFRSKRSGLV RRLWRSRVIP ERDGGDGNGQ SSERNATAVT AEGQRMAQPR RAQEGEGRPV RCCLFAERPG PELPPPPPPP PPGGASPPGP GGGEARSRLV LLERELKAVT YALLKRLKER SLHSLLQAVE SRGGTPGGCV LVARGELRLG AARRPPPHLL LGKLFRWPDL QHPAELKALC ECQSFGAADG PTVCCNPYHF SRLCGPESPP PPYSRLSPND EQKPLDLSDS TLSYTETEAT NSPNVTPGEF SDASTSPDAV KRSHWCNVAY WEHRTRVGRL YTVYEQSVSI FYDLPQGNGF CLGQLNLENR SETVRRTRSK IGYGILLSKE PDGVWAYNRS EHPIFVNSPT LDIPNCRTLI VRKVMPGYSI KVFDYEKSCL LQHTAELDYA DGPYDPNSVR ISFAKGWGPC YSRQFITSCP CWLEILLSNN R
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 668
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Transforming growth factor-beta superfamily receptors signaling occurs through the Smad family of intracellular mediators. SMAD6 is an inhibitory Smad (i-Smad) that negatively regulates signaling downstream of type I transforming growth factor-beta. Acts as a mediator of TGF-beta and BMP anti-inflammatory activities. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. Blocks the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions.
亞細胞定位：

Nucleus.
蛋白家族：

Dwarfin/SMAD family
組織特異性：

Developing heart, eyes and limbs.
數據庫鏈接：

UniGene: Gga.3878