Recombinant Chicken Metalloproteinase inhibitor 2 (TIMP2)

中文名稱：

雞TIMP2重組蛋白
貨號：

CSB-YP023561CH
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

雞TIMP2重組蛋白
貨號：

CSB-EP023561CH
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

雞TIMP2重組蛋白
貨號：

CSB-EP023561CH-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

雞TIMP2重組蛋白
貨號：

CSB-BP023561CH
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

雞TIMP2重組蛋白
貨號：

CSB-MP023561CH
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

TIMP2
Uniprot No.：

O42146
別名：

TIMP2; Metalloproteinase inhibitor 2; Tissue inhibitor of metalloproteinases 2; TIMP-2
種屬：

Gallus gallus (Chicken)
蛋白長度：

Full Length of Mature Protein
表達區域：

27-220
氨基酸序列

CSCS PIHPQQAFCN ADVVIRAKRV SAKEVDSGND IYGNPIKRIQ YEVKQIKMFK GPDQDIEFIY TAPSTEVCGQ PLDTGGKKEY LIAGKSEGDG KMHITLCDLV ATWDSVSPTQ KKSLNQRYQM GCECKISRCL SIPCFVSSSD ECLWTDWAME KIVGGRQAKH YACIKRSDGS CAWYRGMAPP KQEFLDIEDP
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
基因功能參考文獻：
1. Real-time polymerase chain reaction and western blot revealed different expression of MMP-2, -7, -9 and TIMP-2 and -3 on mRNA and protein levels, respectively, as well as activity of MMP-2 and -9 by activity assay in the oviduct parts. PMID: 27342592
2. Protein level of MMP-9 was diminished, while MMP-7 and TIMP-3 were elevated in the oviduct of growing birds. MMP-2 and TIMP-2 protein levels remained constant, with a slight increase in MMP-2 concentration just before reaching maturity. PMID: 26395636
3. Age-related changes of MMP-13 with balance of TIMPs act in concert to effect the controlled testicular remodeling and maturation. PMID: 23218521
4. TIMP-2 expression by cardiac neural crest cells initiates proMMP-2 activation important for their migration. PMID: 15497141
5. distribution of matrix metalloproteinase (MMP)-2, MMP-9, tissue inhibitor of matrix metalloproteinase (TIMP)-1 and TIMP-2 using immunohistochemistry in the ascites syndrome of broiler chickens in a salt-induced experimental model PMID: 16537168
6. These findings collectively show for the first time that multiple MMPs, ADAMs, and TIMPs appear to functionally interact during corneal development. PMID: 17295208
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亞細胞定位：

Secreted.
蛋白家族：

Protease inhibitor I35 (TIMP) family
數據庫鏈接：

KEGG: gga:374178

UniGene: Gga.2965