Recombinant Chicken Heterochromatin-associated protein MENT (SERPINB10)

中文名稱：

雞SERPINB10重組蛋白
貨號：

CSB-YP021066CH
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

雞SERPINB10重組蛋白
貨號：

CSB-EP021066CH
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

雞SERPINB10重組蛋白
貨號：

CSB-EP021066CH-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

雞SERPINB10重組蛋白
貨號：

CSB-BP021066CH
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

雞SERPINB10重組蛋白
貨號：

CSB-MP021066CH
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

SERPINB10
Uniprot No.：

O73790
別名：

SERPINB10; MENT; Heterochromatin-associated protein MENT; Myeloid and erythroid nuclear termination stage-specific protein; Serpin B10
種屬：

Gallus gallus (Chicken)
蛋白長度：

Full length protein
表達區域：

1-410
氨基酸序列

MEQVSASIGN FTVDLFNKLN ETNRDKNIFF SPWSISSALA LTYLAAKGST AREMAEVLHF TEAVRAESSS VARPSRGRPK RRRMDPEHEQ AENIHSGFKE LLTAFNKPRN NYSLRSANRI YVEKTYALLP TYLQLSKKYY KAEPQKVNFK TAPEQSRKEI NTWVEKQTES KIKNLLSSDD VKATTRLILV NAIYFKAEWE VKFQAEKTSI QPFRLSKNKS KPVKMMYMRD TFPVLIMEKM NFKMIELPYV KRELSMFILL PDDIKDGTTG LEQLERELTY ERLSEWADSK MMTETLVDLH LPKFSLEDRI DLRDTLRNMG MTTAFTTNAD FRGMTDKKDL AISKVIHQSF VAVDEKGTEA AAATAVIISF TTSVINHVLK FKVDHPFHFF IRHNKSKTIL FFGRFCCPVE
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

DNA-binding protein that promotes DNA condensation into transcriptionally inactive heterochromatin in terminally differentiated avian blood cells. Promotes tight packing of nucleosomes into spherical clusters by binding to linker DNA and subsequent oligomerization. Acts as a cysteine protease inhibitor towards CTSL (cathepsin L1) and CTSV (cathepsin L2), but does not inhibit serine proteases.
基因功能參考文獻：
1. Data show that a promotion of chromatin folding in terminally differentiated avian blood cells requires the presence of either histone H5 in erythrocytes or myeloid and erythroid nuclear termination stage-specific protein (MENT) in white blood cells. PMID: 21656257
2. MENT was found to undergo structural shifts in the presence of DNA packaged into nucleosomes, but not naked DNA. PMID: 19266095
亞細胞定位：

Nucleus. Chromosome. Note=Associated with chromatin.
蛋白家族：

Serpin family, Ov-serpin subfamily
組織特異性：

Detected in all major blood cell types. Highly expressed in granulocytes (at protein level).
數據庫鏈接：

KEGG: gga:395715

STRING: 9031.ENSGALP00000020960

UniGene: Gga.415