Recombinant Centruroides suffusus Beta-mammal toxin Css2

中文名稱：

Recombinant Centruroides suffusus Beta-mammal toxin Css2
貨號：

CSB-YP362546DRC
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Centruroides suffusus Beta-mammal toxin Css2
貨號：

CSB-EP362546DRC
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Centruroides suffusus Beta-mammal toxin Css2
貨號：

CSB-EP362546DRC-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Centruroides suffusus Beta-mammal toxin Css2
貨號：

CSB-BP362546DRC
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Centruroides suffusus Beta-mammal toxin Css2
貨號：

CSB-MP362546DRC
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

N/A
Uniprot No.：

P08900
別名：

Beta-mammal toxin Css2; Css II; CssII
種屬：

Centruroides suffusus suffusus (Mexican scorpion)
蛋白長度：

full length protein
表達區(qū)域：

1-66
氨基酸序列

KEGYLVSKST GCKYECLKLG DNDYCLRECK QQYGKSSGGY CYAFACWCTH LYEQAVVWPL PNKTCN
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Beta toxin that binds site-4 of sodium channels (Nav) and reduces peak current (observed on Nav1.6/SCN8A (IC(50)=307 nM)), shifts the voltage of activation toward more negative potentials (observed on Nav1.6, Nav1.1 (weak), Nav1.2 (weak), and Nav1.7 (weak)), and induces resurgent currents at negative voltages following brief and strong depolarizations (observed on Nav1.6, Nav1.1 (weak), and Nav1.7 (weak)). A reduction of peak current of Nav1.5/SCN7A has been observed in another study (IC(50)=35-40 nM). This toxin is only active on mammals. It has been shown to bind phospholipids.
亞細胞定位：

Secreted.
蛋白家族：

Long (4 C-C) scorpion toxin superfamily, Sodium channel inhibitor family, Beta subfamily
組織特異性：

Expressed by the venom gland.