Recombinant Bovine Tracheal antimicrobial peptide

中文名稱：

牛N/A重組蛋白
貨號：

CSB-YP328513BO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

牛N/A重組蛋白
貨號：

CSB-EP328513BO
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

牛N/A重組蛋白
貨號：

CSB-EP328513BO-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

牛N/A重組蛋白
貨號：

CSB-BP328513BO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

牛N/A重組蛋白
貨號：

CSB-MP328513BO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

N/A
Uniprot No.：

P25068
別名：

; Tracheal antimicrobial peptide; TAP
種屬：

Bos taurus (Bovine)
蛋白長度：

Cytoplasmic domain
表達(dá)區(qū)域：

27-64
氨基酸序列

NPVS CVRNKGICVP IRCPGSMKQI GTCVGRAVKC CRKK
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Has antibacterial activity in vitro against Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, and Pseudomonas aeruginosa. In addition, the peptide is active against Candida albicans, indicating a broad spectrum of activity.
基因功能參考文獻(xiàn)：
1. Sequencing of exon 2 of the TAP gene from 23 cattle revealed a prevalent non-synonymous single nucleotide polymorphism (SNP) A137G, encoding either serine or asparagine at residue 20 of the mature peptide. PMID: 23333196
2. Twenty four hours post E. coli stimulation, IL1b, IL6, IL8, TNF and LAP gene expression was decreased compared to 6h, whereas TAP and SAA3 expression was further increased to 209- and 3452-fold (P<0.05). PMID: 23200820
3. The results from this study clearly demonstrate the involvement of octamer transcription factor-1 in the regulation of tracheal antimicrobial peptide and lingual antimicrobial peptide expression. PMID: 21674298
4. The production of tracheal antimicrobial peptide in mammary epithelial cells in reponse to bacteria, drugs, and prolactins is reported. PMID: 19181355
亞細(xì)胞定位：

Secreted.
蛋白家族：

Beta-defensin family, LAP/TAP subfamily
組織特異性：

Tracheal epithelium.
數(shù)據(jù)庫鏈接：

KEGG: bta:286837

STRING: 9913.ENSBTAP00000056499

UniGene: Bt.510