Recombinant Bovine Legumain (LGMN)

中文名稱：

牛LGMN重組蛋白
貨號：

CSB-YP012903BO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

牛LGMN重組蛋白
貨號：

CSB-EP012903BO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

牛LGMN重組蛋白
貨號：

CSB-EP012903BO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

牛LGMN重組蛋白
貨號：

CSB-BP012903BO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

牛LGMN重組蛋白
貨號：

CSB-MP012903BO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

LGMN
Uniprot No.：

Q95M12
別名：

LGMN; PRSC1Legumain; EC 3.4.22.34; Asparaginyl endopeptidase; Protease; cysteine 1
種屬：

Bos taurus (Bovine)
蛋白長度：

Full Length of Mature Protein
表達區域：

26-323
氨基酸序列

GGKHW VVIVAGSNGW YNYRHQADAC HAYQIVHRNG IPDEQIIVMM YDDIANSEDN PTPGIVINRP NGSDVYQGVL KDYTGEDVTP KNFLAVLRGD AEAVKGVGSG KVLKSGPRDH VFVYFTDHGA TGILVFPNED LHVKDLNETI RYMYEHKMYQ KMVFYIEACE SGSMMNHLPP DINVYATTAA NPRESSYACY YDEQRSTFLG DWYSVNWMED SDVEDLTKET LHKQYQLVKS HTNTSHVMQY GNKSISAMKL MQFQGLKHQA SSPISLPAVS RLDLTPSPEV PLSIMKRKLM STN
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation. Required for normal lysosomal protein degradation in renal proximal tubules. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
基因功能參考文獻：
1. legumain and TIMP-2 mRNAs were up-regulated in the endometrium during the luteal phase of the oestrous cycle and during early pregnancy PMID: 18449874
亞細胞定位：

Lysosome.
蛋白家族：

Peptidase C13 family
組織特異性：

Detected in kidney (at protein level).
數據庫鏈接：

KEGG: bta:281281

STRING: 9913.ENSBTAP00000053922

UniGene: Bt.8947