Recombinant Bovine Folate receptor alpha (FOLR1)

中文名稱：

牛FOLR1重組蛋白
貨號：

CSB-YP008784BO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

牛FOLR1重組蛋白
貨號：

CSB-EP008784BO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

牛FOLR1重組蛋白
貨號：

CSB-EP008784BO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

牛FOLR1重組蛋白
貨號：

CSB-BP008784BO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

牛FOLR1重組蛋白
貨號：

CSB-MP008784BO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

FOLR1
Uniprot No.：

P02702
別名：

FOLR1Folate receptor alpha; FR-alpha; Folate receptor 1; Folate-binding protein 1; FBP; Milk folate-binding protein
種屬：

Bos taurus (Bovine)
蛋白長度：

Full Length of Mature Protein
表達區域：

20-241
氨基酸序列

A QAPRTPRART DLLNVCMDAK HHKAEPGPED SLHEQCSPWR KNACCSVNTS IEAHKDISYL YRFNWDHCGK MEPACKRHFI QDTCLYECSP NLGPWIREVN QRWRKERVLG VPLCKEDCQS WWEDCRTSYT CKSNWHKGWN WTSGYNQCPV KAAHCRFDFY FPTPAALCNE IWSHSYKVSN YSRGSGRCIQ MWFDPFQGNP NEEVARFYAE NPTSGSTPQG I
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
基因功能參考文獻：
1. summarizes recent biochemical, analytical, food science, and nutritional advances regarding folate-binding protein in milk [REVIEW] PMID: 22369260
2. ligand binding characteristics and aggregation behavior depends on the presence of amphiphatic substances [folate binding protein] PMID: 12516784
亞細胞定位：

Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Cytoplasmic vesicle. Cytoplasmic vesicle, clathrin-coated vesicle. Endosome. Apical cell membrane.
蛋白家族：

Folate receptor family
組織特異性：

Detected in milk (at protein level).
數據庫鏈接：

KEGG: bta:516067

STRING: 9913.ENSBTAP00000027602

UniGene: Bt.62067