Recombinant Bluetongue virus 10 Non-structural protein P8 (S10)

中文名稱：

Recombinant Bluetongue virus 10 Non-structural protein P8(S10)
貨號：

CSB-YP362404BHQ
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Bluetongue virus 10 Non-structural protein P8(S10)
貨號：

CSB-EP362404BHQ
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Bluetongue virus 10 Non-structural protein P8(S10)
貨號：

CSB-EP362404BHQ-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Bluetongue virus 10 Non-structural protein P8(S10)
貨號：

CSB-BP362404BHQ
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Bluetongue virus 10 Non-structural protein P8(S10)
貨號：

CSB-MP362404BHQ
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

S10
Uniprot No.：

P08363
別名：

Segment-10; Non-structural protein P8; Non-structural protein NS3) [Cleaved into: Non-structural protein NS3A]
種屬：

Bluetongue virus 10 (isolate USA) (BTV 10)
蛋白長度：

full length protein
表達區域：

1-229
氨基酸序列

MLSGLIQRFE EEKMKHNQDR VEELSLVRVD DTISQPPRYA PSAPMPSSMP TVALEILDKA MSNTTGATQT QKAEKAAFAS YAEAFRDDVR LRQIKRHVNE QILPKLKSDL SELKKKRAII HTTLLVAAVV ALLTSVCTLS SDMSVAFKIN GTKTEVPSWF KSLNPMLGVV NLGATFLMMV CAKSERALNQ QIDMIKKEVM KKQSYNDAVR MSFTEFSSIP LDGFEMPLT
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Plays a role in the inhibition of host innate immune response. Interacts with host OPTN and thus inhibits the recruitment of TBK1 to the host Golgi apparatus. In turn, downstream partner IRF3 cannot be activated and IFN-beta production is impaired.; Facilitates viral particle release either by increasing plasma membrane permeability through a viroporin-like activity or by viral budding.
基因功能參考文獻：
1. Biochemical characterization of recombinant NS3 protein revealed that it forms SDS-resistant dimers and high-order oligomers (hexamer and/or octamer) under reducing or non-reducing conditions. PMID: 26318174
2. S10 gene segments have 822 nucleotides and encodes two proteins, NS3 and NS3A. PMID: 16276888
3. Mutations in NS3 affect virus egress during virus infection. PMID: 19369335
亞細胞定位：

Host cell membrane; Multi-pass membrane protein. Host Golgi apparatus.
蛋白家族：

Orbivirus NS3 family
數據庫鏈接：

KEGG: vg:2943154