Recombinant Arabidopsis thaliana Protein SUPPRESSOR OF npr1-1, CONSTITUTIVE 1 (SNC1), partial

中文名稱：

擬南芥SNC1重組蛋白
貨號：

CSB-YP517811DOA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

擬南芥SNC1重組蛋白
貨號：

CSB-EP517811DOA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

擬南芥SNC1重組蛋白
貨號：

CSB-EP517811DOA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

擬南芥SNC1重組蛋白
貨號：

CSB-BP517811DOA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

擬南芥SNC1重組蛋白
貨號：

CSB-MP517811DOA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

SNC1
Uniprot No.：

O23530
別名：

SNC1; BAL; At4g16890; dl4475c; FCAALL.51; Protein SUPPRESSOR OF npr1-1; CONSTITUTIVE 1; AtSNC1; Disease resistance RPP5-like protein; Probable NAD(+) hydrolase SNC1; EC 3.2.2.6
種屬：

Arabidopsis thaliana (Mouse-ear cress)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Disease resistance protein of the TIR-NB-LRR-type. Part of the RPP5 locus that contains a cluster of several paralogous disease resistance (R) genes. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. Probably acts as a NAD(+) hydrolase (NADase): in response to activation, catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide; NAD(+) cleavage triggering a defense system that promotes cell death. Expression regulated by MOS1 at chromatin level. Nuclear localization of SNC1 is essential for its activity. ABA deficiency can rescue high-temperature inhibition of SNC1-mediated defense responses.
基因功能參考文獻：
1. SNC1 is a major mediator of defense response modulated by SIZ1 and that SNC1 is a crucial target for fine-tuning plant defense responses. PMID: 28409535
2. This study provides structural platform to investigate AtSNC1-TIR mediated signaling pathway of plant immune responses. PMID: 27818198
3. MUSE13 and MUSE14 contribute to the turnover of nucleotide-binding domain and leucine-rich repeat-containing (NLR) immune receptors SNC1 and RPS2. PMID: 26867179
4. SNC1 protein accumulated in taf15b mutant, suggesting that TAF15b contributes to SNC1 homeostasis through posttranscriptional mechanisms. PMID: 26713351
5. abnormal pavement cell morphogenesis in cpr1 is accompanying with the aberrant arrangement of cytoskeleton. PMID: 26193674
6. SNC1 exhibits a few distinct N-terminal isoforms generated through alternative initiation and N-terminal acetylation. PMID: 25966763
7. nuclear SNC1 is necessary for rapid activation of downstream defense responses of plant immunity PMID: 25237053
8. MOS2 contributes to proper splicing of SNC1 transcript, redundantly with MOS2H. PMID: 23803746
9. Abscisic acid deficiency enhances disease resistance mediated by SNC1 at high temperature. PMID: 22454454
10. Study report the gene expression pattern and subcellular localization of MOS1. In addition, study analyzes and discusses the roles of DNA and histone methylation in mos1-mediated suppression of SNC1 expression. PMID: 21350329
11. MODIFIER OF snc1, 1 (MOS1) regulates the expression of SUPPRESSOR OF npr1-1, CONSTITUTIVE1 (SNC1), which encodes a Toll/interleukin receptor-nucleotide binding site-leucine-rich repeat type of R protein in Arabidopsis PMID: 20439546
12. overexpression of TPR1 constitutively activates SNC1-mediated immune responses. PMID: 20647385
13. We isolated Arabidopsis mutants with point mutation in SNC1 that retain disease resistance at a higher growth temperature PMID: 20368979
14. We propose that the high degree of variation in SNC1-related sequences among Arabidopsis natural accessions follows the two-step mechanism observed in the bal variant: gene duplication followed by hypermutation. PMID: 19797048
15. One mutant that suppresses snc1-mediated constitutive resistance is modifier of snc1 5 (mos5), which carries a 15-bp deletion in UBA1. PMID: 17217463
16. The regulation of SNC1 possibly exemplifies a universally complex control of R genes to ensure a repression of R activation under nonstress conditions and a robust activation of defense responses once the R gene is induced. PMID: 17977156
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亞細胞定位：

Cytoplasm. Microsome. Nucleus.
蛋白家族：

Disease resistance NB-LRR family
組織特異性：

Expressed in guard cells and epidermal cells, but not detected in mesophyll cells.
數據庫鏈接：

KEGG: ath:AT4G16890

STRING: 3702.AT4G16890.1

UniGene: At.43451