otop1 Antibody

^{Rare Species}

說明書

產品詳情

Uniprot No.：

Q7ZWK8
基因名：

otop1
別名：

Otopetrin-1 otop1
反應種屬：

Danio rerio (Zebrafish) (Brachydanio rerio)
免疫原：

Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) otop1 protein (406-518aa)
免疫原種屬：

Danio rerio (Zebrafish) (Brachydanio rerio)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Affinity-chromatography
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Proton-selective channel that specifically transports protons into cells. Proton channel activity is only weakly-sensitive to voltage. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. In the vestibular system of the inner ear, required for the formation and function of otoconia, which are calcium carbonate crystals that sense gravity and acceleration. Probably acts by maintaining the pH appropriate for formation of otoconia. May be involved in sour taste perception in sour taste cells by mediating entry of protons within the cytosol.
基因功能參考文獻：
1. Otopetrin 1 in zebrafish may be involved in the protein trafficking of components required for formation of biominerals in the ear. PMID: 15480759
2. Results demonstrate that otopetrin 1 has an essential and conserved role in the timing of formation and the size and shape of the developing otolith. PMID: 15581873
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

Otopetrin family
數據庫鏈接：

KEGG: dre:322893

UniGene: Dr.77257

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