ZWINT Antibody
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中文名稱：ZWINT兔多克隆抗體
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貨號：CSB-PA527261ESR1HU
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規格：￥440
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圖片：
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Western blot
All lanes: ZWINT antibody at 8.93μg/ml
Lane 1: Hela whole cell lysate
Lane 2: Mouse liver tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 32, 26 kDa
Observed band size: 32 kDa -
Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA527261ESR1HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA527261ESR1HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) ZWINT Polyclonal antibody
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Uniprot No.：
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基因名：ZWINT
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別名：Human ZW10 interacting protein 1 antibody; HZwint 1 antibody; HZwint1 antibody; KNTC 2 AP antibody; KNTC2AP antibody; MGC 117174 antibody; MGC117174 antibody; ZW10 interacting kinetochore protein antibody; ZW10 interacting protein 1 antibody; ZW10 interactor antibody; ZW10 interactor; kinetochore protein antibody; ZW10-interacting protein 1 antibody; ZWINT 1 antibody; ZWINT antibody; Zwint-1 antibody; ZWINT_HUMAN antibody; ZWINT1 antibody
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宿主：Rabbit
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反應種屬：Human, Mouse
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免疫原：Recombinant Human ZW10 interactor protein (1-277AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase.
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基因功能參考文獻：
- ZW10 interactor was frequently decreased in hepatocellular carcinoma. PMID: 30198401
- Our results provide the first evidence that Zwint-1 is required to correct erroneous kinetochore-microtubule attachment and regulate spindle checkpoint function during meiosis. PMID: 26486467
- the E3 ubiquitin ligase terf causes protein degradation of ZWINT and negatively regulates cell proliferation PMID: 22023800
- These studies identify zwint-1 as a novel AurB substrate required for kinetochore assembly and for proper spindle assembly checkpoint silencing at metaphase PMID: 21775627
- hZwint-1 bridges the inner and outer kinetochore: identification of the kinetochore localization domain and the hZw10-interaction domain PMID: 21345172
- show that ZW10 interacting protein-1(Zwint-1) is required and is sufficient for kinetochore localization of Zeste White 10 (ZW10) in HeLa cells PMID: 15485811
- Stable hZW10 kinetochore residency at prometaphase kinetochores is dependent on its interaction with hZwint-1, and is essential for mitotic checkpoint arrest. PMID: 18268100
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亞細胞定位：Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase.
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數據庫鏈接：
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