WDPCP Antibody

文獻引用 (1) 說明書

中文名稱：

WDPCP兔多克隆抗體
貨號：

CSB-PA528516LA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA528516LA01HU at dilution of 1:100

Immunofluorescence staining of MCF-7 cells with CSB-PA528516LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) WDPCP Polyclonal antibody
Uniprot No.：

O95876
基因名：

WDPCP
別名：

Bardet-Biedl syndrome 15 protein antibody; Chromosome 2 open reading frame 86 antibody; DKFZp686C12204 antibody; Fritz antibody; FRITZ_HUMAN antibody; hFrtz antibody; WD repeat containing protein C2orf86 antibody; WD repeat-containing and planar cell polarity effector protein antibody; WD repeat-containing and planar cell polarity effector protein fritz homolog antibody; WDPCP antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human WD repeat-containing and planar cell polarity effector protein fritz homolog protein (621-737AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，WDPCP Antibody (CSB-PA528516LA01HU)，的標記方式是Non-conjugated。對于WDPCP Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA528516LB01HU	WDPCP Antibody, HRP conjugated	ELISA
FITC	CSB-PA528516LC01HU	WDPCP Antibody, FITC conjugated
Biotin	CSB-PA528516LD01HU	WDPCP Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Together with FUZ and WDPCP proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies.
基因功能參考文獻：
1. Inflammatory cytokines cause reduced WDPCP expression, which contributes to impaired ciliogenesis in human rhinosinusitis. PMID: 28001338
2. study linked mutations in Fritz to Bardet-Biedl and Meckel-Gruber syndromes, a notable link given that other genes mutated in these syndromes also influence collective cell movement and ciliogenesis PMID: 20671153
相關疾病：

Bardet-Biedl syndrome 15 (BBS15); Congenital heart defects, hamartomas of tongue, and polysyndactyly (CHDTHP)
亞細胞定位：

Cell membrane. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body.
蛋白家族：

WD repeat fritz family
數據庫鏈接：

HGNC: 28027

OMIM: 217085

KEGG: hsa:51057

STRING: 9606.ENSP00000272321

UniGene: Hs.414952

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