USP6NL Antibody, FITC conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) USP6NL Polyclonal antibody
Uniprot No.：

Q92738
基因名：

USP6NL
別名：

KIAA0019 antibody; Related to the N terminus of tre antibody; Related to the N-terminus of tre antibody; RN tre antibody; RN-tre antibody; RNTRE antibody; TRE2NL antibody; US6NL_HUMAN antibody; USP6 N terminal like antibody; USP6 N terminal like protein antibody; USP6 N-terminal-like protein antibody; USP6NL antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human USP6 N-terminal-like protein (387-693AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.
基因功能參考文獻：
1. Genome-wide significant (GWS) associations in single-nucleotide polymorphism (SNP)-based tests (P < 5 x 10(-8)) were identified for SNPs in PFDN1/HBEGF, USP6NL/ECHDC3, and BZRAP1-AS1. PMID: 28183528
2. Rab5 signals to the actin cytoskeleton through RN-tre, a previously identified Rab5-specific GTPase-activating protein; RN-tre interacts with both F-actin and actinin-4, an F-actin bundling protein PMID: 15152255
亞細胞定位：

Golgi apparatus. Cytoplasmic vesicle.
組織特異性：

Widely expressed.
數據庫鏈接：

HGNC: 16858

OMIM: 605405

KEGG: hsa:9712

STRING: 9606.ENSP00000277575

UniGene: Hs.498661

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