USP47 Antibody
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中文名稱：USP47兔多克隆抗體
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貨號：CSB-PA045692
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規(guī)格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA045692(USP47 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA045692(USP47 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：USP47
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別名：Deubiquitinating enzyme 47 antibody; TFRP antibody; Trf TATA binding protein related factor proximal homolog antibody; Trf TATA binding protein related factor proximal homolog Drosophila antibody; Ubiquitin carboxyl-terminal hydrolase 47 antibody; Ubiquitin specific peptidase 47 antibody; Ubiquitin specific processing protease 47 antibody; Ubiquitin specific protease 47 antibody; Ubiquitin thioesterase 47 antibody; Ubiquitin thiolesterase 47 antibody; Ubiquitin-specific-processing protease 47 antibody; UBP47_HUMAN antibody; USP47 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse
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免疫原：Fusion protein of Human USP47
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 IHC 1:25-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level.
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基因功能參考文獻：
- these results suggest that USP47 may play distinct roles in ubiquitin-mediated cellular processes via de-ubiquitinating enzymes activity. PMID: 26115687
- miR-204-5p acts as a tumor suppressor in gastric cancer through inhibiting USP47 and RAB22A. PMID: 25429829
- USP47 is a deubiquitinase that prevents beta-catenin ubiquitination. PMID: 26169834
- Data indicate that E-cadherin ubiquitination consistently increases after depletion of kinesin-like protein KIFC3 or ubiquitin-specific protease USP47. PMID: 25253721
- The results of this study indicated that USP47 plays a crucial role in the control of axonal growth during neuronal development by antagonizing CHIP-mediated katanin-p60 degradation. PMID: 23904609
- USP47 has a role in regulating DNA repair and maintaining genome integrity PMID: 21362556
- USP47, a novel beta-Trcp interactor, regulates cell growth and survival, potentially providing a novel target for anticancer therapies. PMID: 19966869
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亞細胞定位：Cytoplasm.
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蛋白家族：Peptidase C19 family
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組織特異性：Expressed in skeletal muscle, heart and testis.
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數(shù)據(jù)庫鏈接：
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