UBLCP1 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) UBLCP1 Polyclonal antibody
Uniprot No.：

Q8WVY7
基因名：

UBLCP1
別名：

CPUB1 antibody; CTD like phosphatase domain containing protein antibody; CTD phosphatase like with ubiquitin domain 1 antibody; FLJ25267 antibody; MGC10067 antibody; Nuclear proteasome inhibitor UBLCP1 antibody; UBCP1_HUMAN antibody; Ubiquitin like domain containing CTD phosphatase 1 antibody; Ubiquitin-like domain-containing CTD phosphatase 1 antibody; UBLCP1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Ubiquitin-like domain-containing CTD phosphatase 1 protein (2-318AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.
基因功能參考文獻：
1. Data show that UBLCP1 selectively binds to the 26S proteasome non-ATPase regulatory subunit 13 (19S regulatory particle) in regulating proteasome assembly. PMID: 28539385
2. the high-resolution solution structure of the UBL domain of human UBLCP1 and its interaction with Rpn1 PMID: 23667555
3. UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity PMID: 21949367
亞細胞定位：

Nucleus. Note=Colocalizes with nuclear proteasomes.
組織特異性：

Broadly expressed, with highest levels in placenta, lung, testis and ovary. Up-regulated in tumor tissues.
數據庫鏈接：

HGNC: 28110

OMIM: 609867

KEGG: hsa:134510

STRING: 9606.ENSP00000296786

UniGene: Hs.591733

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