UBE2Z Antibody

說(shuō)明書

產(chǎn)品詳情

Uniprot No.：

Q9H832
基因名：

UBE2Z
別名：

FLJ13855 antibody; GC17P044341 antibody; HOYS7 antibody; Uba6 specific E2 conjugating enzyme 1 antibody; UBA6 specific enzyme E2 antibody; Uba6-specific E2 conjugating enzyme 1 antibody; UBE2Z antibody; UBE2Z_HUMAN antibody; Ubiquitin carrier protein Z antibody; Ubiquitin conjugating enzyme E2 Z antibody; Ubiquitin conjugating enzyme E2Z antibody; Ubiquitin protein ligase Z antibody; Ubiquitin-conjugating enzyme E2 Z antibody; Ubiquitin-protein ligase Z antibody; Use1 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human UBE2Z
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Catalyzes the covalent attachment of ubiquitin to other proteins. Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation.
基因功能參考文獻(xiàn)：
1. The SNP rs46522 in UBE2Z gene is associated with the risk of coronary Artery disease in the individuals of Chinese Han descent with type 2 diabetes and is of synergistic effect with Body mass index. PMID: 28840129
2. we found that USE1 proteins were frequently overexpressed in human lung cancer. Furthermore, overexpression of USE1 promoted in vivo and in vitro proliferation, migration, and invasion. PMID: 28376205
3. Association of UBE2Z single nucleotide polymorphism rs46522 with the susceptibility to coronary artery disease in an Iranian population. PMID: 26602883
4. UBE2Z was widely expressed in human tissues and is located on chromosome 17q21. PMID: 17160626
5. In tissue culture cells, Uba6 is required for charging a previously uncharacterized Uba6-specific E2 (Use1), whereas Ube1 is required for charging the cell-cycle E2s Cdc34A and Cdc34B PMID: 17597759
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亞細(xì)胞定位：

Cytoplasm. Nucleus.
蛋白家族：

Ubiquitin-conjugating enzyme family
組織特異性：

Widely expressed. Highly in placenta, pancreas, spleen and testis.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 25847

OMIM: 611362

KEGG: hsa:65264

STRING: 9606.ENSP00000354201

UniGene: Hs.514297

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