UBE2V2 Antibody, Biotin conjugated
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中文名稱：UBE2V2兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA025484DD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) UBE2V2 Polyclonal antibody
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Uniprot No.：
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基因名：UBE2V2
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別名：1 alpha 25 dihydroxyvitamin D3 inducible antibody; DDVit 1 antibody; DDVIT1 antibody; EDAF-1 antibody; EDAF1 antibody; EDPF-1 antibody; EDPF1 antibody; Enterocyte differentiation associated factor EDAF 1 antibody; Enterocyte differentiation promoting factor antibody; Enterocyte differentiation-associated factor 1 antibody; Enterocyte differentiation-promoting factor 1 antibody; Methyl methanesulfonate sensitive 2 antibody; MMS 2 antibody; MMS2 antibody; MMS2 homolog antibody; UB2V2_HUMAN antibody; UBE2V 2 antibody; UBE2V2 antibody; Ubiquitin conjugating enzyme E2 variant 2 antibody; Ubiquitin conjugating enzyme E2v2 antibody; Ubiquitin-conjugating enzyme E2 variant 2 antibody; UEV 2 antibody; UEV2 antibody; Vitamin D3 inducible protein antibody; Vitamin D3-inducible protein antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Ubiquitin-conjugating enzyme E2 variant 2 protein (2-145AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
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基因功能參考文獻：
- Functional analysis of selected regulated proteins revealed that knockdown of HNRPD, PHB2 and UB2V2 can increase HCMV replication, while knockdown of A4 and KSRP resulted in decreased HCMV replication. PMID: 25910425
- suppression of hMMS2 reverses L-OHP tolerance in differentiated human colorectal carcinoma cells by promoting apoptosis PMID: 24846979
- UBE2v2 signalling through PCNA ubiquitination is not required for immunoglobulin diversification in DT40 cells. PMID: 15725630
- Insight into the influence of protein dynamics on the affinity of ubiquitin for Mms2. PMID: 15952783
- Mms2 physical association with ubiquitin is correlated with its ability to promote Lys63-linked ubiquitin chain assembly PMID: 17964296
- These results point to a high level of redundancy in the DNA damage tolerance pathway and suggest the existence of another hMMS2 variant (hMMSv) or complex that can compensate for its loss. PMID: 18284681
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蛋白家族：Ubiquitin-conjugating enzyme family
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組織特異性：Detected in placenta, colon, liver and skin. Detected at very low levels in most tissues.
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數據庫鏈接：
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