Tmprss4 Antibody

產品詳情

產品名稱：

Rabbit anti-Mus musculus (Mouse) Tmprss4 Polyclonal antibody
Uniprot No.：

Q8VCA5
基因名：

Tmprss4
別名：

Tmprss4 antibody; Cap2 antibody; Transmembrane protease serine 4 antibody; EC 3.4.21.- antibody; Channel-activating protease 2 antibody; mCAP2 antibody
宿主：

Rabbit
反應種屬：

Mouse
免疫原：

Recombinant Mouse Transmembrane protease serine 4 protein (52-435AA)
免疫原種屬：

Mus musculus (Mouse)

標記方式：

Non-conjugated

本頁面中的產品，Tmprss4 Antibody (CSB-PA844988LA01MO)，的標記方式是Non-conjugated。對于Tmprss4 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA844988LB01MO	Tmprss4 Antibody, HRP conjugated	ELISA
FITC	CSB-PA844988LC01MO	Tmprss4 Antibody, FITC conjugated
Biotin	CSB-PA844988LD01MO	Tmprss4 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC.
基因功能參考文獻：
1. The lung fibrotic response evaluated at 28 days after bleomycin injury was markedly attenuated in the haplodeficient and deficient TMPRSS4 mice. PMID: 29529050
2. Epithelial Sodium Channel-Mediated Sodium Transport Is Not Dependent on the Membrane-Bound Serine Protease CAP2/Tmprss4 PMID: 26309024
3. Progression and metastatic potential of several cancers is concordant with an increased expression of TMPRSS4. PMID: 22944691
4. TMPRSS4 primarily activates ENaC by cleaving basic residues within the tract gammaK173-K186 distal to the furin cleavage site, thereby releasing a previously defined key inhibitory tract encompassing gammaR158-F168 from the gamma-subunit. PMID: 21993886
亞細胞定位：

Cell membrane; Single-pass type II membrane protein.; [Transmembrane protease serine 4 catalytic chain]: Secreted.
蛋白家族：

Peptidase S1 family
數據庫鏈接：

KEGG: mmu:214523

STRING: 10090.ENSMUSP00000034599

UniGene: Mm.436756

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