TULP3 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) TULP3 Polyclonal antibody
Uniprot No.：

O75386
基因名：

TULP3
別名：

MGC45295 antibody; Tubby like protein 3 antibody; Tubby related protein 3 antibody; Tubby-like protein 3 antibody; Tubby-related protein 3 antibody; TUBL 3 antibody; TUBL3 antibody; TULP 3 antibody; TULP3 antibody; TULP3_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Tubby-related protein 3 protein (1-260AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis. During adipogenesis, regulates ciliary trafficking of FFAR4 in preadipocytes.
基因功能參考文獻：
1. Data demonstrated that pancreatic cancer patients exhibiting high transcriptional levels of TULP3 showed a poor overall survival rate. PMID: 24668219
亞細胞定位：

Nucleus. Cell membrane. Cell projection, cilium. Cytoplasm. Secreted.
蛋白家族：

TUB family
組織特異性：

Expressed at high levels in testis, ovaries, thyroid, and spinal chord.
數據庫鏈接：

HGNC: 12425

OMIM: 604730

KEGG: hsa:7289

STRING: 9606.ENSP00000380321

UniGene: Hs.655333

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