TUBB6 Antibody

文獻引用 (2) 說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) TUBB6 Polyclonal antibody
Uniprot No.：

Q9BUF5
基因名：

TUBB6
別名：

tubulin beta-6 chain-like antibody; class V beta-tubulin antibody; HsT1601 antibody; TBB6_HUMAN antibody; TUBB-5 antibody; TUBB6 antibody; Tubulin beta 6 chain antibody; tubulin beta 6 class V antibody; tubulin beta class V antibody; tubulin beta MGC4083 antibody; Tubulin beta-6 antibody; Tubulin beta-6 chain antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Tubulin beta-6 chain protein (1-446AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，TUBB6 Antibody (CSB-PA880105LA01HU)，的標記方式是Non-conjugated。對于TUBB6 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA880105LB01HU	TUBB6 Antibody, HRP conjugated	ELISA
FITC	CSB-PA880105LC01HU	TUBB6 Antibody, FITC conjugated
Biotin	CSB-PA880105LD01HU	TUBB6 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
基因功能參考文獻：
1. Findings enlarge the spectrum of tubulinopathies and emphasize that mutations of TUBB6 should be considered in patients with congenital non-progressive facial palsy. PMID: 29016863
2. TUBB6 is an inhibitor of pyroptosis. PMID: 24173717
3. Data indicate that leucine-rich repeat kinase 2 (LRRK2) selectively interacts with three beta-tubulin isoforms: TUBB, TUBB4, and TUBB6. PMID: 24275654
4. betaV-tubulin expression is a potentially promising prognostic marker of malignancy. PMID: 22903939
5. in colorectal cancer patients, there was a link between poor survival, the expression of TUBB3/TUBB6, and androgen receptor only in females PMID: 22438565
6. The TUBB6 expression was largely decreased in most tumors. PMID: 20191564
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亞細胞定位：

Cytoplasm, cytoskeleton.
蛋白家族：

Tubulin family
組織特異性：

Ubiquitous. Maximal expression in breast and lung, where it represents around 10% of all beta-tubulins. Largely decreased expression in most cancerous tissues.
數據庫鏈接：

HGNC: 20776

OMIM: 615103

KEGG: hsa:84617

STRING: 9606.ENSP00000318697

UniGene: Hs.193491

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