TTI2 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) TTI2 Polyclonal antibody
Uniprot No.：

Q6NXR4
基因名：

TTI2
別名：

C8orf41 antibody; CH041_HUMAN antibody; TELO2 interacting protein 2provided antibody; TTI2 antibody; Uncharacterized protein C8orf41 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human TELO2-interacting protein 2 protein (159-264AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.
基因功能參考文獻：
1. The findings emphasises the role of the TTI2 gene in the etiology of intellectual disability. PMID: 23956177
2. TTI1 and TTI2 protect cells from spontaneous DNA damage, and are required for the establishment of the intra-S and G2/M checkpoint. PMID: 20810650
相關疾病：

Mental retardation, autosomal recessive 39 (MRT39)
蛋白家族：

TTI2 family
數據庫鏈接：

HGNC: 26262

OMIM: 614426

KEGG: hsa:80185

STRING: 9606.ENSP00000353971

UniGene: Hs.742048

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