TRIM38 Antibody
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中文名稱：TRIM38兔多克隆抗體
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貨號：CSB-PA275171
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規格：￥2024
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圖片：
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Western blot analysis of extracts from RAW264.7 cells and LOVO cells, using TRIM38 antibody.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) TRIM38 Polyclonal antibody
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Uniprot No.：
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基因名：TRIM38
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Synthesized peptide derived from internal of Human TRIM38.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:3000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：E3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling.
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基因功能參考文獻：
- Data suggest that mRNA/protein levels of NLRP6 are down-regulated in synovial tissues and synoviocytes of rheumatoid arthritis (RA) patients compared to osteoarthritis patients; NLRP6 provides docking site to facilitate interaction between TAB2/3 and TRIM38 in RA synoviocytes in response to TNFalpha. (NLRP6 = ; TAB2/3 = transforming growth factor-b-activated kinase 1-binding protein 2/3; TRIM38 = tripartite motif 38) PMID: 28295271
- TRIM38 may act as a novel negative regulator for TLR3-mediated type I interferon signaling by targeting TRIF for degradation PMID: 23056470
- NF-kappaB is activated in response to TRIM38. PMID: 21789858
- Enterovirus 71 infection induces degradation of TRIM38. PMID: 21306652
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組織特異性：Ubiquitous.
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數據庫鏈接：
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