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中文名稱：
TPK1兔多克隆抗體
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貨號：
CSB-PA024103GA01HU
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規格：
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其他：
產品詳情
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Uniprot No.：
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基因名：
TPK1
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別名：
hTPK1 antibody; Placental protein 20 antibody; PP20 antibody; Thiamin pyrophosphokinase 1 antibody; Thiamine diphosphokinase antibody; Thiamine kinase antibody; Thiamine pyrophosphokinase 1 antibody; THMD5 antibody; TPK1 antibody; TPK1_HUMAN antibody
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宿主：
Rabbit
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反應種屬：
Human,Mouse,Rat
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免疫原：
Human TPK1
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免疫原種屬：
Homo sapiens (Human)
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抗體亞型：
IgG
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純化方式：
Antigen Affinity Purified
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濃度：
It differs from different batches. Please contact us to confirm it.
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保存緩沖液：
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：
Liquid
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應用范圍：
ELISA,WB,IHC
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Protocols：
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儲存條件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點詳情
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功能：
Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate.
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基因功能參考文獻：
- Mutation analysis of TPK1 uncovered three missense, one splice-site, and one frameshift mutation resulting in decreased TPK protein levels PMID: 22152682
- findings indicate the importance of the Sp1 transcription factor cis-element in regulating the human thiamin pyrophosphokinase gene (hTPK1) gene expression PMID: 16262001
- Genomic variations in either the fetal or maternal TPK1 gene could contribute to variability of birth weight in normal humans. PMID: 17295612
- This is the first report on the primary sequence for mammalian thiamin pyrophosphokinase, a protein that catalyzes the pyrophosphorylation of thiamin with adenosine 5'-triphosphate to form thiamin pyrophosphate. PMID: 10567383
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相關疾病：
Thiamine metabolism dysfunction syndrome 5, episodic encephalopathy type (THMD5)
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蛋白家族：
Thiamine pyrophosphokinase family
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組織特異性：
Detected in heart, kidney, testis, small intestine and peripheral blood leukocytes, and at very low levels in a variety of tissues.
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數據庫鏈接：
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