TNNT1 Antibody
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中文名稱：TNNT1兔多克隆抗體
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貨號(hào)：CSB-PA024015GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：TNNT1
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別名：ANM antibody; MGC104241 antibody; NEM5 antibody; Skeletal antibody; Slow antibody; slow skeletal muscle antibody; Slow skeletal muscle troponin T antibody; sTnT antibody; Tnnt1 antibody; TNNT1_HUMAN antibody; TNT antibody; TnTs antibody; Troponin T antibody; Troponin T slow skeletal muscle antibody; Troponin T type 1 (skeletal slow) antibody; troponin T1 skeletal slow antibody; Troponin T1, slow skeletal type antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human TNNT1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
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基因功能參考文獻(xiàn)：
- High TNNT1 expression is associated with breast cancer. PMID: 30031058
- This study describes the first TNNT1 mutation that transmits in an autosomal dominant fashion to cause nemaline myopathy. PMID: 29178646
- investigated the effects of one of these mutations, K247R of TnT, on the picosecond dynamics of the Tn core domain (Tn-CD), consisting of TnC, TnI and TnT2 (183-288 residues of TnT), by carrying out the quasielastic neutron scattering measurements on the reconstituted Tn-CD containing either the wild-type TnT2 (wtTn-CD) or the mutant TnT2 (K247R-Tn-CD) in the absence and presence of Ca(2+) PMID: 28923663
- Data suggest that mutations in troponin C (TnC, A8V) and troponin T (TnT, delta14-TnT) found in patients with hypertrophic cardiomyopathy together fully stabilize the active M state of regulated actin (the actin-tropomyosin-troponin complex). PMID: 28530094
- pathogenesis of TNNT1 myopathies PMID: 27429059
- Copeptin and troponin T measurement could potentially improve the prehospital diagnostic and prognostic classification of patients with a suspected AMI. PMID: 27903076
- TNNT1 genetic and epigenetic variations are associated with HDL-C levels and coronary artery disease. PMID: 26950807
- Three homologous genes have evolved in vertebrates to encode three muscle type-specific TnT isoforms: TNNT1 for slow skeletal muscle TnT, TNNT2 for cardiac muscle TnT, and TNNT3 for fast skeletal muscle TnT. PMID: 26774798
- Nemaline body myopathy Palestinian patients were found to have a novel mutation in troponin T1. PMID: 26296490
- troponin T and creatinine kinase isoenzyme (CK-MB) have roles in combined renal and myocardial injuries in asphyxiated infants PMID: 24625749
- Biopsy-proven acute and viral myocarditis is associated with elevated concentrations of hs-TnT. PMID: 24781421
- Troponin T1 blood levels had a positive association with increased risk for hypertrophic cardiomyopathy. PMID: 24020864
- TNNT1 DNA methylation levels were positively correlated with mean HDL particle size, HDL-phospholipid, HDL-apolipoprotein AI, HDL-C and TNNT1 expression levels. PMID: 23244308
- Human slow skeletal troponin T (HSSTnT) isoforms, despite being homologues of cardiac TnT may display distinct functional properties in muscle regulation. PMID: 22977240
- analysis of parameters of oxygen-dependent metabolism of neutrophils by NBT test and levels of vWF antigen in the serum can be used for predicting the risk of unfavorable outcome in patients with ACS and normal troponin T PMID: 22448368
- In heart failure patients with normal ejection fraction, highly sensitive troponin T and heart fatty acid binding protein are elevated independent of coronary artery disease. PMID: 21729325
- baseline cTnT levels are higher in patients with MPI evidence of reversible myocardial ischaemia than those without reversible ischaemia PMID: 22239123
- carotid-femoral pulse wave and office pulse pressure are associated with minimally elevated hsTnT levels in the elderly PMID: 21784424
- the hypertrophic phenotype associated with the TnT mutations can be characterized by a significant increase in disorder of rigor cross-bridges. PMID: 21683708
- Elevated serum troponin T levels are associated with different conditions related to the severity of hypertrophic cardiomyopathy. PMID: 21111984
- Cardiac troponin T and creatine kinase have roles in infarct size and left ventricular function after acute myocardial infarction PMID: 21448949
- The occurrence of myocardial infarction is associated with elevated troponin T levels. PMID: 19916752
- Among athletees, faster runners demonstrate significantly stronger cardoac TnT releases and inflammation signs. PMID: 20380359
- troponin-T mutations were responsible for 3% of the hypertrophic cardiomyopathy cases in our study population PMID: 20038417
- Troponin T may have a role in pulmonary embolism progeresion to death PMID: 19541721
- TNT is a biochemical marker of susceptibility to hypoxia in infants of type 1 diabetic mothers. PMID: 19690080
- Data suggest that inefficient incorporation into myofilament is responsible for the instability of mutant slow troponin T in Amish nemaline myopathy. PMID: 15665378
- Report adaptation by alternative RNA splicing of slow troponin T isoforms in type 1 but not type 2 Charcot-Marie-Tooth disease. PMID: 18579801
- slow TnT was encoded by two different transcripts in significantly different ratios in myotonic dystrophy type 1 and myotonic dystrophy type 2 muscles. PMID: 19326042
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相關(guān)疾病：Nemaline myopathy 5 (NEM5)
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蛋白家族：Troponin T family
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