TMEM2 Antibody, HRP conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) TMEM2 Polyclonal antibody
Uniprot No.：

Q9UHN6
基因名：

TMEM2
別名：

KIAA1412 antibody; TMEM 2 antibody; tmem2 antibody; TMEM2_HUMAN antibody; Transmembrane protein 2 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Cell surface hyaluronidase protein (734-866AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Unlike its mouse ortholog has no catalytic hyaluronic acid-degrading activity, but acts as a regulator of hyaluronan (HA) metabolism through regulation of expression of CEMIP and HAS2, two enzymes involved in HA depolymerization and HA synthesis, respectively.
基因功能參考文獻：
1. TMEM2 inhibits Hepatitis b virus infection in HepG2 and HepG2.2.15 by activating the JAK-STAT signaling pathway. PMID: 27253403
2. our findings lead us to propose that TMEM2 may not only mediate the pathologic effects of SOX4 on cancer progression but also potentially its contributions to embryonic development PMID: 27328729
3. Results showed that missense mutations in transmembrane protein 2 p.Ser1254Asn, interferon alpha 2 p.Ala120Thr, its regulator NLR family member X1 p.Arg707Cys, and complement component 2 p.Glu318Asp were associated with chronic hepatitis B. PMID: 22610944
亞細胞定位：

Cell membrane; Single-pass type II membrane protein.
蛋白家族：

TMEM2 family
組織特異性：

Widely expressed.
數據庫鏈接：

HGNC: 11869

OMIM: 605835

KEGG: hsa:23670

STRING: 9606.ENSP00000366243

UniGene: Hs.494146

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