TECPR2 Antibody

說(shuō)明書(shū)

中文名稱：

TECPR2兔多克隆抗體
貨號(hào)：

CSB-PA023369LA01HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA023369LA01HU at dilution of 1:100

Immunofluorescent analysis of PC-3 cells using CSB-PA023369LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) TECPR2 Polyclonal antibody
Uniprot No.：

O15040
基因名：

TECPR2
別名：

TECPR2 antibody; KIAA0297 antibody; KIAA0329 antibody; Tectonin beta-propeller repeat-containing protein 2 antibody; WD repeat-containing protein KIAA0329/KIAA0297 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Tectonin beta-propeller repeat-containing protein 2 protein (516-783AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁(yè)面中的產(chǎn)品，TECPR2 Antibody (CSB-PA023369LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于TECPR2 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

標(biāo)記方式	貨號(hào)	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA023369LB01HU	TECPR2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA023369LC01HU	TECPR2 Antibody, FITC conjugated
Biotin	CSB-PA023369LD01HU	TECPR2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Probably plays a role as positive regulator of autophagy.
基因功能參考文獻(xiàn)：
1. Whole exome sequencing in an Italian pedigree suggests involvement of TECPR2 in a complex form of progressive motor neuron disease. PMID: 27406698
2. The discovery of additional TECPR2 utations in non-Bukharian patients implies that this disease might be more common than previously appreciated PMID: 26542466
3. Results show that TECPR2 associates with several trafficking components as SEC24D and cooperates with LC3C to regulate ER exit sites and ER export suggesting that TECPR2 functions as molecular scaffold linking early secretion pathway and autophagy. PMID: 26431026
4. The discovered TECPR2 mutation implicates autophagy, a central intracellular mechanism, in spastic paraparesis. PMID: 23176824
相關(guān)疾病：

Spastic paraplegia 49, autosomal recessive (SPG49)
蛋白家族：

WD repeat KIAA0329 family
組織特異性：

Detected in skin fibroblast (at protein level).
數(shù)據(jù)庫(kù)鏈接：

HGNC: 19957

OMIM: 615000

KEGG: hsa:9895

STRING: 9606.ENSP00000352510

UniGene: Hs.195667

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