TBPL1 Antibody
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中文名稱：TBPL1兔多克隆抗體
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貨號：CSB-PA023240ESR1HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA023240ESR1HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA023240ESR1HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) TBPL1 Polyclonal antibody
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Uniprot No.：
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基因名：TBPL1
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別名：21 kDa TBP-like protein antibody; 21kDa TBP like protein antibody; Second TBP of unique DNA antibody; Second TBP of unique DNA protein antibody; STUD antibody; TATA box binding protein like protein 1 antibody; TATA box binding protein-related factor 2 antibody; TATA box-binding protein-like protein 1 antibody; TATA box-binding protein-related factor 2 antibody; TBP like 1 antibody; TBP like protein antibody; TBP related factor 2 antibody; TBP-like factor antibody; TBP-like protein 1 antibody; TBP-related factor 2 antibody; TBP-related protein antibody; tbpl1 antibody; TBPL1_HUMAN antibody; TLF antibody; TLP antibody; TRF2 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human TATA box-binding protein-like protein 1 protein (1-186AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes. Seems to also mediate the transcription of NF1. Does not bind the TATA box.
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基因功能參考文獻：
- TLP Prevents p53 Degradation through Disrupting the p53-MDM2 Interaction. PMID: 28082682
- The interaction of TBP-like protein with TFIIA is essential to suppress proteasome-dependent turnover of TBP-like protein PMID: 27696626
- miR18a exhibits a protective role in colorectal cancer (CRC) via inhibiting proliferation, invasion and migration of CRC cells by directly targeting the TBPL1 gene. PMID: 26398009
- results suggest that activation of the p21 upstream promoter is mediated by interaction between specific regions of TLP and p53 PMID: 24594805
- Western blotting and immunohistochemistry both indicated a higher TBPL1 protein expression level in colorectal cancer tissue. siRNA for TBPL1 transfection obviously slowed down the cell proliferation in both SW-620 and HT-29 cells. PMID: 24870791
- TLP mediates p53-governed transcriptional activation of the p21 upstream promoter. PMID: 22511763
- Data show that during interphase, endogenous or exogenously expressed TRF2 is located almost exclusively in the nucleolus PMID: 15269281
- TLF is a functional regulator of transcription with targets distinct from those of TBP. PMID: 15767669
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亞細胞定位：Cytoplasm. Nucleus.
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蛋白家族：TBP family
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組織特異性：Ubiquitously expressed, with highest levels in the testis and ovary.
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數據庫鏈接：
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