SYNJ2 Antibody
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中文名稱：SYNJ2兔多克隆抗體
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貨號：CSB-PA023017GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：
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別名：4 antibody; 5-trisphosphate 5-phosphatase 2 antibody; Inositol phosphate 5' phosphatase 2 antibody; INPP 5H antibody; INPP5H antibody; KIAA0348 antibody; MGC44422 antibody; SJ2 antibody; Synaptic inositol 1 4 5 trisphosphate 5 phosphatase 2 antibody; Synaptic inositol-1 antibody; Synaptojanin-2 antibody; Synaptojanin2 antibody; SYNJ 2 antibody; Synj2 antibody; SYNJ2_HUMAN antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human SYNJ2
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Inositol 5-phosphatase which may be involved in distinct membrane trafficking and signal transduction pathways. May mediate the inhibitory effect of Rac1 on endocytosis.
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基因功能參考文獻(xiàn)：
- Results, combined with previous studies, suggest that rs9365723, located on SYNJ2, is associated with the risk of CRC in a Chinese population. PMID: 26616230
- Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer. PMID: 25605973
- The genetic interactions associated with ILVatrophy rate in this study may be mapping variants inSYNJ2andPI4KAthat interact to decrease synthesisof PIP. PMID: 24077433
- Src-mediated phosphorylation of SYNJ2 contributes to invadopodia formation. PMID: 23076136
- SYNJ2 is a novel gene in which variation is potentially associated with cognitive abilities. PMID: 22045296
- Single nucleotide polymorphisms in SYNJ2 are associated with personality disorders. PMID: 22213687
- SYNJ2 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
- Since Syn 2 is a phosphatidylinositol 4,5-biphosphatase involved in cell growth and rearrangement of actin filaments, the increased Syn 2 expression may correlate with the hairy cell leukemia etiology or the characteristic morphologic alterations. PMID: 14562116
- contributes to the role of Rac1 in cell invasion and migration by regulating the formation of invadopodia and lamellipodia PMID: 15548694
- Identification of inactivating mutations in the JAK1, SYNJ2, and CLPTM1 genes in prostate cancer cells PMID: 16102578
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亞細(xì)胞定位：Cytoplasm. Cell membrane. Membrane raft. Cell junction, synapse, presynapse. Cytoplasm, cytoskeleton.
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蛋白家族：Synaptojanin family; Inositol 1,4,5-trisphosphate 5-phosphatase family
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數(shù)據(jù)庫鏈接：
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