SUPT20H Antibody
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中文名稱：SUPT20H兔多克隆抗體
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貨號：CSB-PA394854
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規格：￥1090
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圖片：
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Western Blot analysis of mouse-kidney cells using Antibody diluted at 1000
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：AA667204 antibody; AI450544 antibody; bA421P11.4 antibody; C13 antibody; C13orf19 antibody; D3Ertd300e antibody; FA48A_HUMAN antibody; FAM48A antibody; FP757 antibody; p38-interacting protein antibody; p38IP antibody; Protein FAM48A antibody; RGD1307812 antibody; SPT20 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Synthetic peptide from AA range: 231-280
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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純化方式：The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB,ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-10000ELISA:1:10000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail. Required for starvation-induced ATG9A trafficking during autophagy.
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基因功能參考文獻：
- provide the first report that p38-p38IP is required for the Snail-induced E-cadherin down-regulation and cell invasion in HNSCC PMID: 27531877
- p38IP inhibits ubiquitination-induced GCN5 degradation and therefore promotes alpha-tubulin acetylation, facilitating spindle formation and G2/M progression. PMID: 24220028
- hSPT20 and other hSAGA subunits, together with RNA polymerase II, are specifically recruited to genes induced by endoplasmic reticulum (ER) stress. PMID: 19114550
- Manipulation of p38IP and p38alpha alters mAtg9 localization, suggesting p38alpha regulates, through p38IP, the starvation-induced mAtg9 trafficking to forming autophagosomes. PMID: 19893488
- Novel transcription factors identified in human CD34 antigen-positive hematopoietic stem cells. PMID: 12070015
- C13orf19 mRNA is down-regulated in matched prostate tissues compared to prostate carcinoma tissues PMID: 15978328
- C13orf19 is expressed independently of the androgen. No interaction between C13orf19 and p38MAPK was identified. PMID: 16685401
- mRNA is down-regulated in human prostate cancer, also described as C13 PMID: 11340631
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亞細胞定位：Nucleus.
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蛋白家族：SPT20 family
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組織特異性：Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate tissues.
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數據庫鏈接：
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