Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
May play a role in cholesterol transfer to late endosomes. May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions. May play a role in protecting FBXW7 isoform 3 from degradation.
基因功能參考文獻:
[review] Stomatin family member STOML1 is oligomeric; it mostly localizes to membrane domains and has been shown to modulate ion channel activity. PMID: 21501885
Stomatin-like protein-1 interacts with stomatin and is targeted to late endosomes PMID: 19696025
亞細胞定位:
Membrane; Single-pass type III membrane protein. Late endosome membrane. Membrane raft. Cell membrane; Single-pass type III membrane protein. Cytoplasmic vesicle.
蛋白家族:
Band 7/mec-2 family
組織特異性:
Ubiquitously expressed at low levels. Expression is highest in brain.