STK17A Antibody
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中文名稱：STK17A兔多克隆抗體
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貨號：CSB-PA288472
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA288472(STK17A Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA288472(STK17A Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200) -
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Raji cells, 293T cells, Primary antibody: CSB-PA288472(STK17A Antibody) at dilution 1/900, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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其他：
產品詳情
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Uniprot No.：
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基因名：STK17A
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別名：DAP kinase-related apoptosis-inducing protein kinase 1 antibody; death-associated protein kinase-related 1 antibody; DRAK1 antibody; EC 2.7.11.1 antibody; Serine / threonine kinase 17a death associated protein kinase related 1 antibody; Serine/threonine kinase 17a antibody; Serine/threonine protein kinase 17a antibody; Serine/threonine-protein kinase 17A antibody; ST17A_HUMAN antibody; STK17 A antibody; STK17A antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthetic peptide of Human STK17A
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 WB 1:500-1:2000 IHC 1:25-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species.
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基因功能參考文獻：
- These findings suggest that DRAK1 translocates in response to stimuli and induces apoptosis through its interaction with specific binding partners, p53 and/or ANT2. PMID: 29397938
- the present study was the first to find localization of STK17A in normal bile canaliculi. PMID: 26305096
- DRAK1 was predominantly localized in the cytoplasm and bound to Smad3, thereby interrupting Smad3/Smad4 complex formation, which is the core process for the induction of tumor suppressor genes by TGF-beta1 PMID: 25531329
- STK17A provides a proliferative and survival advantage to GBM cells PMID: 24312360
- When analyzing STK17A haplotypes distribution, we found association between TGGTC, TAGTC and AAGAT haplotypes and risk to develop SLE PMID: 23860322
- identified STK17A as a novel direct target of p53 and a modulator of cisplatin toxicity and reactive oxygen species in testicular cancer cells. PMID: 21489989
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亞細胞定位：Nucleus.
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蛋白家族：Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily
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組織特異性：Highly expressed in placenta. Lower levels in heart, lung, skeletal muscle, kidney and pancreas.
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數據庫鏈接：
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