ST8SIA2 Antibody
-
中文名稱：ST8SIA2兔多克隆抗體
-
貨號：CSB-PA022775GA01HU
-
規格：￥3,900
-
其他：
產品詳情
-
Uniprot No.：
-
基因名：ST8SIA2
-
別名：ST8SIA2 antibody; SIAT8B antibody; STX antibody; Alpha-2,8-sialyltransferase 8B antibody; EC 2.4.99.- antibody; Sialyltransferase 8B antibody; SIAT8-B antibody; Sialyltransferase St8Sia II antibody; ST8SiaII antibody; Sialyltransferase X antibody; STX antibody
-
宿主：Rabbit
-
反應種屬：Human,Mouse,Rat
-
免疫原：Human ST8SIA2-Specific
-
免疫原種屬：Homo sapiens (Human)
-
抗體亞型：IgG
-
純化方式：Antigen Affinity purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
-
產品提供形式：Liquid
-
應用范圍：ELISA,WB
-
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：May transfer sialic acid through alpha-2,8-linkages to the alpha-2,3-linked and alpha-2,6-linked sialic acid of N-linked oligosaccharides of glycoproteins and may be involved in PSA (polysialic acid) expression.
-
基因功能參考文獻：
- The ST8SIA2 risk haplotype copy number did not show any differential effects on white matter in schizophrenia. PMID: 29353880
- impairment of the regulated expression of ST8SIA2 and the resulting downstream effects on gene products by these two intronic single nucleotide polymorphism contribute to the development of these psychiatric disorders. PMID: 27565727
- ST8SiaII role in the invasiveness and metastasis of small cell lung cancer cells PMID: 28004110
- the relationships between psychiatric disorders and polySia and/or ST8SIA2 PMID: 27105834
- Data indicate a possible role of STX polysialyltransferase (ST8SIA2) in the common susceptibility of schizophrenia and bipolar I disorder (BD-I). PMID: 26418860
- Our study showed interesting sex-specific associations between ST8SIAII and schizophrenia. PMID: 24070986
- the role of ST8SIA2 sequence variation affecting polysialic acid-NCAM formation in 48 Caucasian cases with bipolar disorder PMID: 24651862
- translational modification of the neural cell adhesion molecule NCAM and the polysialyltransferase ST8SiaII in mammalian semen involves polysialic acid PMID: 23671285
- Expression of ST8SIA2 in omental fat at baseline was significantly associated with weight loss after Roux-en-Y gastric bypass. PMID: 23643386
- that variation the ST8SIA2 gene is associated with increased risk to mental illness PMID: 22693595
- NCAM and polySia are expressed and developmentally regulated in chick corneas. Both membrane-associated and soluble NCAM isoforms are expressed in chick corneas. PMID: 22281821
- ST8SIA2 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
- STX(G421A) shows a dramatic decrease in polySia synthetic activity on NCAM, whereas STX(C621G) does not; polySia shows a dopamine (DA) binding activity PMID: 21464126
- This study provided that ST8SIA2 are associated with Bipolar I in the Han Chinese population. PMID: 20386566
- SIAT8B has a role in neural development and sialic acid synthesis on NCAM PMID: 12138100
- SIAT8B gene is involved in schizophrenia in the Japanese. PMID: 16229822
顯示更多
收起更多
-
亞細胞定位：Golgi apparatus membrane; Single-pass type II membrane protein.
-
蛋白家族：Glycosyltransferase 29 family
-
組織特異性：Highly expressed in fetal brain, kidney and heart and to a much lesser extent in adult heart and thymus.
-
數據庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
